Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704147 | 0.79 | ALDH1A1 (0.34) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL106923 | 0.76 | TDP1 (0.37) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL106516 | 0.76 | TSHR (0.36) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL708488 | 0.76 | ALDH1A1 (0.35) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL705272 | 0.76 | ESR1 (0.38) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL309052 | 0.74 | ESR1 (0.37) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL705119 | 0.74 | ESR1 (0.37) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL706260 | 0.74 | ESR1 (0.37) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL713414 | 0.74 | ESR1 (0.37) | TDP1ALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL28458112 | 0.73 | TSHR (0.41) | ALDH1A1L3MBTL1TSHRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662456-B | Preparation method of siloxane polymer | 中国科学院化学研究所 | 2021-08-03 | — | — | CN | disclosed |
| CN-111662456-A | Preparation method of siloxane polymer | 中国科学院化学研究所 | 2020-09-15 | — | — | CN | disclosed |