Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18019440 | 0.89 | ESR1 (0.33) | ESR1ESR2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL705977 | 0.87 | — | — | |
| SCHEMBL705272 | 0.83 | ESR1 (0.38) | ESR1ESR2ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL27730607 | 0.81 | — | — | |
| SCHEMBL27792570 | 0.81 | SLC6A2 (0.33) | — | |
| SCHEMBL713414 | 0.81 | ESR1 (0.37) | ESR1ESR2ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL28626711 | 0.80 | MEN1 (0.43) | ESR1ESR2ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL4266063 | 0.79 | ABCB1 (0.35) | ESR1ESR2NPSR1TSHRLMNA | |
| SCHEMBL15483444 | 0.78 | — | — | |
| SCHEMBL106516 | 0.78 | TSHR (0.36) | ESR1ESR2ALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | FITZHUGH ANTHONY | 2007-04-19 | — | — | US | claimed |
| EP-1436018-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003026717-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-03 | — | — | WO | claimed |
| US-4039666-A | ANTICONVULSANT PHENYLSILANES | DOW CORNING CORPORATION (US) | 1977-08-02 | — | — | US | claimed |
| US-9520576-B2 | Gas barrier film and electronic apparatus | Konica Minolta, Inc. (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20150064401-A1 | GAS BARRIER FILM AND ELECTRONIC DEVICE | Konica Minolta, Inc. (JP) | 2015-03-05 | — | — | US | disclosed |
| US-20140322478-A1 | GAS BARRIER FILM AND ELECTRONIC APPARATUS | Konica Minolta, Inc. (JP) | 2014-10-30 | — | — | US | disclosed |
| CN-103492499-A | Silica-coating-forming composition for use with inkjets, method for forming silica coating, semiconductor device, and solar-cell system | HITACHI CHEMICAL CO LTD | 2014-01-01 | — | — | CN | disclosed |
| US-8124239-B2 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8093419-B2 | Method of producing organosilicon compound | JSR CORPORATION (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20100261925-A1 | METHOD FOR PRODUCING SILICON COMPOUND | JSR CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261925-A1 | METHOD FOR PRODUCING SILICON COMPOUND | JSR CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-1545798-A1 | CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20040260048-A1 | Organosilicon compound - curing composition and silicone-base coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1436018-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-07-14 | — | — | EP | disclosed |
| US-20040077757-A1 | Coating composition for use in producing an insulating thin film | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-04-22 | — | — | US | disclosed |
| WO-2004012874-A1 | CROSS-LINKED NITRIC OXIDE-RELEASING POLYAMINE COATED SUBSTRATES, COMPOSITIONS COMPRISING SAME AND METHOD OF MAKING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003026717-A1 | NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-03 | — | — | WO | disclosed |
| EP-1276807-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | Dow Corning Corporation (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083608-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | NOS2, NOS1, NOS3 | ESR1 1016/4885ESR2 1178/4885ALDH1A1 2127/4885 |
| US-20100261925-A1 | METHOD FOR PRODUCING SILICON COMPOUND | GMNN, GEMIN5, SEPTIN7 | ESR1 3712/4885ESR2 3674/4885ALDH1A1 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.