SCHEMBL708488

SCHEMBL708488

CC(C)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
TSHR P16473 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 2/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
CA4 P22748 1/20 0.31
TAAR1 Q96RJ0 3/20 0.30
SLC6A2 P23975 2/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706260 0.98 ESR1 (0.37) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL1315375 0.82 TSHR (0.32) ESR1TSHRADRA2AADRA2BADRA2C
SCHEMBL1313033 0.82 TSHR (0.32) ESR1TSHRADRA2AADRA2BADRA2C
SCHEMBL106923 0.80 TDP1 (0.37) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL106516 0.80 TSHR (0.36) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL705272 0.80 ESR1 (0.38) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL309052 0.78 ESR1 (0.37) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL705119 0.78 ESR1 (0.37) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL713414 0.78 ESR1 (0.37) ALDH1A1L3MBTL1ESR1ESR2TSHR
SCHEMBL704147 0.78 ALDH1A1 (0.34) ALDH1A1L3MBTL1ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641835-B Method for producing carbamate 国立研究开发法人产业技术综合研究所 2021-07-20 CN disclosed
EP-3508473-B1 METHOD FOR PRODUCING CARBAMIC ACID ESTER AIST (JP) 2021-05-26 EP disclosed
US-10752579-B2 Production method of carbamic acid ester NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2020-08-25 US disclosed
US-10749047-B2 Solar cell element and method for manufacturing solar cell element KYOCERA CORPORATION (JP) 2020-08-18 US disclosed
CN-111492492-A Solar cell element 京瓷株式会社 2020-08-04 CN disclosed
US-20190221682-A1 SOLAR CELL ELEMENT AND METHOD FOR MANUFACTURING SOLAR CELL ELEMENT KYOCERA CORPORATION (JP) 2019-07-18 US disclosed
EP-3508473-A1 METHOD FOR PRODUCING CARBAMIC ACID ESTER National Institute of Advanced Industrial Science and Technology (JP) 2019-07-10 EP disclosed
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-20 US disclosed
CN-109844959-A SOLAR CELL ELEMENT AND METHOD FOR MANUFACTURING SOLAR CELL ELEMENT 京瓷株式会社 2019-06-04 CN disclosed
CN-109641835-A Method for producing carbamate 国立研究开发法人产业技术综合研究所 2019-04-16 CN disclosed
CN-1891757-A Silica film forming material, silica film and method of manufacturing the same FUJITSU LTD (JP) 2007-01-10 CN disclosed
US-20060269724-A1 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-11-30 US disclosed
US-6787193-B2 DECOMPOSITION OF AN ORGANOSILICON COMPOUND JSR CORPORATION (JP) 2004-09-07 US disclosed
US-20040077757-A1 Coating composition for use in producing an insulating thin film ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-04-22 US disclosed
US-20030008155-A1 Method for the formation of silica film, silica film, insulating film, and semiconductor device JSR CORPORATION (JP) 2003-01-09 US disclosed
EP-1267395-A2 Method for the formation of silica film, silica film, insulating film, and semiconductor device JSR Corporation (JP) 2002-12-18 EP disclosed
US-5576406-A ACRYLATE POLYMERS FOR PAINTS, ADHESIVES OR SEALS DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-11-19 US disclosed
US-4388449-A THERMOPLASTIC, DIELECTRICS, HOLD OUT AGENTS FOR HEAT RECOVERABLE MATERIALS RAYCHEM LIMITED (GB) 1983-06-14 US disclosed
US-4387196-A DIELECTRICS RAYCHEM LIMITED (GB) 1983-06-07 US disclosed
US-4265801-A FIREPROOF DIELECTRIC SACKETS FOR WIRES ETC. RAYCHEM LIMITED (GB) 1981-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190185420-A1 PRODUCTION METHOD OF CARBAMIC ACID ESTER CA2, CA7, CA4 ALDH1A1 3215/4885L3MBTL1 3678/4885ESR1 1852/4885
US-10752579-B2 Production method of carbamic acid ester CA2, CA7, CA4 ALDH1A1 3215/4885L3MBTL1 3678/4885ESR1 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.