Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878156 | 0.78 | ALDH1A1 (0.59) | ALDH1A1GAAGFERHPGDMEN1 | |
| SCHEMBL2844178 | 0.77 | ALDH1A1 (0.38) | ALDH1A1GAAGFERLMNAHPGD | |
| SCHEMBL2848196 | 0.77 | PSEN1 (0.46) | ALDH1A1GAAGFERLMNACYP4F2 | |
| SCHEMBL31511904 | 0.76 | HTT (0.61) | ALDH1A1GAAGFERLMNAHPGD | |
| SCHEMBL10876611 | 0.76 | HTT (0.61) | ALDH1A1GAAGFERLMNAHPGD | |
| SCHEMBL3668882 | 0.74 | GAA (0.72) | ALDH1A1GAAGFERLMNAHPGD | |
| SCHEMBL29446278 | 0.74 | GAA (0.72) | ALDH1A1GAAGFERLMNAHPGD | |
| SCHEMBL2436585 | 0.73 | GAA (0.76) | ALDH1A1GAAGFERLMNAHPGD | |
| Methyl Alcohol SCHEMBL27946196 | 0.73 | GAA (0.70) | ALDH1A1GAAGFERLMNAHPGD | |
| SCHEMBL7042014 | 0.71 | GABRA1 (0.63) | ALDH1A1GAAGFERLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |