Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696279 | 0.98 | SENP1 (0.52) | SENP1ACHERAPGEF4ESR1ESR2 | |
| SCHEMBL6246454 | 0.88 | SENP1 (0.56) | SENP1ACHEESR1ESR2HSD17B1 | |
| Water SCHEMBL11499545 | 0.86 | SENP1 (0.54) | SENP1ACHEESR1ESR2HSD17B1 | |
| SCHEMBL28876445 | 0.86 | ALDH1A1 (0.50) | SENP1ACHERAPGEF4ESR1ESR2 | |
| SCHEMBL6382158 | 0.85 | ALDH1A1 (0.40) | RAPGEF4TSHRALDH1A1 | |
| SCHEMBL14173108 | 0.85 | ACHE (0.54) | SENP1ACHEESR1ESR2HSD17B1 | |
| SCHEMBL7639577 | 0.84 | SENP1 (0.44) | SENP1ACHERAPGEF4ESR1ESR2 | |
| SCHEMBL7809088 | 0.84 | SENP1 (0.52) | SENP1ACHEESR1ESR2GAA | |
| SCHEMBL14451020 | 0.83 | ESR2 (0.61) | ESR1ESR2HSD17B1HSD17B2ABL1 | |
| SCHEMBL8617658 | 0.82 | SENP1 (0.42) | SENP1ACHERAPGEF4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358498-A | Tetraaryloxy IVB group binuclear metal complex and preparation and application thereof | 万华化学集团股份有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-109023322-B | Water-based membrane liquid replacing phosphating liquid and preparation method thereof | 青岛恒信达化工有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111675661-A | Diaryl pyrimidine HIV-1 reverse transcriptase inhibitor containing trans double bond and preparation method and application thereof | 山东大学 | 2020-09-18 | — | — | CN | claimed |
| CN-111675694-A | Oxime group-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2020-09-18 | — | — | CN | claimed |
| CN-111187222-A | Substituted pyrimidine derivative and preparation method and application thereof | 山东大学 | 2020-05-22 | — | — | CN | claimed |
| CN-106000325-B | A kind of magnetism decoloring material and preparation method thereof | 四川理工学院 | 2019-11-26 | — | — | CN | claimed |
| CN-107778255-B | A kind of Diarylmiazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2019-10-25 | — | — | CN | claimed |
| WO-2019196370-A1 | FIVE-MEMBERED NON AROMATIC RING-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | 山东大学 | 2019-10-17 | — | — | WO | claimed |
| WO-2019196369-A1 | THIAZOLO-PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | 山东大学 | 2019-10-17 | — | — | WO | claimed |
| CN-107746452-B | Palladium load different-phase catalyst based on micro--mesoporous phenolic resin and preparation method thereof | 大连理工大学 | 2019-10-11 | — | — | CN | claimed |
| CN-106117242-A | Tetrahydric thiapyran miazines derivative and preparation method and application | 山东大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106000325-A | Magnetic decoloration material and preparation method thereof | 四川理工学院 | 2016-10-12 | — | — | CN | claimed |
| CN-105754057-A | P containing phenolic resin polymer and preparation method thereof | 中国科学院大连化学物理研究所 | 2016-07-13 | — | — | CN | claimed |
| CN-105294550-A | 6-substitute diaryl pyridine derivative and preparing method and application thereof | UNIV SHANDONG | 2016-02-03 | — | — | CN | claimed |
| CN-104610794-A | Phosphor-nitrogen intumescent flame retardant, and synthetic method and applications thereof | INST ADVANCED TECHNOLOGY UNIV SCIENCE & TECHNOLOGY CHINA | 2015-05-13 | — | — | CN | claimed |
| CN-104610525-A | Halogen-free environment-friendly polyurethane oil paint and preparation method thereof | NANJING TONGYUAN NEW MATERIAL TECHNOLOGY CO LTD | 2015-05-13 | — | — | CN | claimed |
| CN-104530078-A | Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof | UNIV SHANDONG | 2015-04-22 | — | — | CN | claimed |
| CN-103450158-B | 2, 4 ,6 - tri-substituted pyrimidine derivative and preparing method and application thereof | UNIV SHANDONG | 2015-04-08 | — | — | CN | claimed |
| CN-103450158-A | 2, 4 ,6 - tri-substituted pyrimidine derivative and preparing method and application thereof | UNIV SHANDONG | 2013-12-18 | — | — | CN | claimed |
| CN-102887887-A | 2-(1-substituted piperidine-4-amino)-6-(substituted phenylamine/phenol) pyridine derivatives and preparation method and application thereof | UNIV SHANDONG | 2013-01-23 | — | — | CN | claimed |