SCHEMBL8617658

SCHEMBL8617658

Cc1cc(C)c(-c2ccc(O)cc2)c(C(C)(C)c2cc(C)cc(C)c2-c2ccc(O)cc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.42
POLB P06746 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.39
TYR P14679 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.39
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
CSNK2A1 P68400 1/20 0.38
ESR1 P03372 8/20 0.38
ESR2 Q92731 7/20 0.38
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
AR P10275 1/20 0.38
HPGD P15428 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
HTR6 P50406 1/20 0.38
ESRRG P62508 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28077434 0.89 TYR (0.48) SENP1POLBALDH1A1CA2TYR
SCHEMBL2846017 0.82 SENP1 (0.54) SENP1POLBALDH1A1RAPGEF4CSNK2A2
SCHEMBL28696279 0.81 SENP1 (0.52) SENP1RAPGEF4CSNK2A2CSNK2BCSNK2A1
SCHEMBL27526925 0.79 ALDH1A1 (0.54) SENP1POLBALDH1A1CA2TYR
SCHEMBL30712607 0.78 KIF11 (0.43) ALDH1A1ARGAA
SCHEMBL8617662 0.77 ESR1 (0.54) SENP1ALDH1A1TYRESR1ESR2
SCHEMBL187251 0.76 GABRA1 (0.46) SENP1ALDH1A1CA2ESR1ESR2
SCHEMBL29599213 0.74 AR (0.35) AR
SCHEMBL28876445 0.74 ALDH1A1 (0.50) SENP1POLBALDH1A1RAPGEF4CSNK2A2
SCHEMBL28225673 0.73 LMNA (0.54) SENP1POLBALDH1A1TYRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584624-B1 Segmented N-alkylated polyurethane amides BAYER AG (DE) 1998-04-29 EP disclosed
EP-0520227-B1 Flame resistant thermoplastic polyamide moulding compositions BASF AG (DE) 1996-01-17 EP disclosed
US-5434209-A Phenolic compounds BASF AKTIENGESELLSCHAFT (DE) 1995-07-18 US disclosed
US-5391641-A Molding materials BAYER AKTIENGESELLSCHAFT (DE) 1995-02-21 US disclosed
EP-0584624-A2 Segmented N-alkylated polyurethane amides BAYER AG (DE) 1994-03-02 EP disclosed
EP-0224847-B1 REINFORCED POLYAMIDES WITH IMPROVED FLOWING PROPERTIES BAYER AG (DE) 1993-09-08 EP disclosed
US-5212224-A Impact modified polyamides with diene or acrylic rubbers BAYER AKTIENGESELLSCHAFT (DE) 1993-05-18 US disclosed
EP-0520227-A1 Flame resistant thermoplastic polyamide moulding compositions BASF Aktiengesellschaft (DE) 1992-12-30 EP disclosed
US-5010146-A Heat resistance, mechanical strength MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-23 US disclosed
EP-0347169-A2 Polyester carbonate copolymers processes for preparing same and polyester resin compositions containing said copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-12-20 EP disclosed
US-4745146-A INJECTION MOLDING MATERIALS WITH BISPHENOL COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
EP-0240887-A2 Flowable mouldings based on polyamides BAYER AG (DE) 1987-10-14 EP disclosed
EP-0224847-A2 Reinforced polyamides with improved flowing properties BAYER AG (DE) 1987-06-10 EP disclosed