Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454838 | 0.88 | RAB9A (0.51) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL28458534 | 0.87 | RAB9A (0.50) | ALDH1A1MAPTNPSR1KDM4EGAA | |
| SCHEMBL28462858 | 0.85 | L3MBTL1 (0.55) | ALDH1A1MAPTNPSR1KDM4EL3MBTL1 | |
| SCHEMBL28466895 | 0.83 | L3MBTL1 (0.55) | ALDH1A1MAPTNPSR1KDM4EGAA | |
| SCHEMBL28899426 | 0.82 | HDAC1 (0.54) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL28460815 | 0.82 | NR4A2 (0.56) | ALDH1A1MAPTKDM4EKMT2ARAB9A | |
| SCHEMBL4364200 | 0.82 | RAB9A (0.71) | ALDH1A1MAPTNPSR1KDM4EGAA | |
| SCHEMBL28463974 | 0.82 | LMNA (0.54) | ALDH1A1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL28454840 | 0.81 | L3MBTL1 (0.55) | ALDH1A1MAPTNPSR1GAARAB9A | |
| SCHEMBL28455043 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665985-B | Polysubstituted indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-09-29 | — | — | CN | disclosed |