Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14639033 | 0.84 | LMNA (0.50) | LMNAKMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL28319996 | 0.83 | TSHR (0.50) | NPC1RAB9ALMNAKMT2APOLB | |
| SCHEMBL27152360 | 0.83 | PKM (0.48) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL29487353 | 0.83 | POLB (0.46) | RAB9AHPGDERCC5FEN1KMT2A | |
| SCHEMBL27874622 | 0.83 | KMT2A (0.42) | NPC1RAB9AHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27981110 | 0.83 | CTSD (0.51) | NPC1RAB9AHPGDLMNAKMT2A | |
| SCHEMBL13734754 | 0.83 | POLB (0.46) | RAB9AHPGDERCC5FEN1KMT2A | |
| SCHEMBL28463115 | 0.81 | HPGD (0.40) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL4346405 | 0.80 | PLK1 (0.50) | NPC1RAB9AHPGDLMNAKMT2A | |
| SCHEMBL991197 | 0.79 | ERCC5 (0.50) | NPC1RAB9AHPGDERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898213-B | Polysubstituted 1, 3-diene supported ring compound and application thereof | 中国科学院上海药物研究所 | 2022-11-04 | — | — | CN | disclosed |
| CN-112898213-A | Polysubstituted 1, 3-diene supported ring compound and application thereof | 中国科学院上海药物研究所 | 2021-06-04 | — | — | CN | disclosed |
| CN-110156721-A | Utilize diazotate, cyclic ethers, amine and CO2The method of synthesis of carbamates | 华南理工大学 | 2019-08-23 | — | — | CN | disclosed |