SCHEMBL28463197

SCHEMBL28463197

O=C(O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ GAA P10253 1/20 0.46
▸ TYR P14679 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ PTPN1 P18031 1/20 0.45
▸ LGALS8 O00214 1/20 0.45
▸ PYGB P11216 1/20 0.45
▸ SLC28A3 Q9HAS3 1/20 0.44
▸ SYNJ2 O15056 1/20 0.44
▸ IGF2R P11717 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29217353 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL9684872 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL28453332 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL11216298 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL28790781 0.98 LGALS8 (0.46) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL9559641 0.98 LGALS8 (0.46) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL9559995 0.98 LGALS8 (0.46) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL8994862 0.87 LGALS3 (0.53) TYRPTPN1LGALS8IGF2R
SCHEMBL28902343 0.86 PYGB (0.50) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL28453329 0.86 PYGB (0.50) L3MBTL1GAATYRMAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111712507-A Method for improving oral bioavailability of drugs 药物有限公司 2020-09-25 — — CN disclosed
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