Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | PPARA | Q07869 | 3/20 | 0.77 |
| ▸ | PPARG | P37231 | 1/20 | 0.77 |
| ▸ | PPARD | Q03181 | 1/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allyleugenol SCHEMBL29401211 | 0.93 | ALDH1A1 (0.77) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Allyleugenol SCHEMBL2779960 | 0.93 | ALDH1A1 (0.77) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| SCHEMBL18244599 | 0.90 | ALDH1A1 (0.63) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL1869396 | 0.88 | ALDH1A1 (1.00) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL113794 | 0.88 | ALDH1A1 (1.00) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL29376951 | 0.88 | ALDH1A1 (1.00) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL5564539 | 0.86 | ALDH1A1 (0.96) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL27951383 | 0.86 | ALDH1A1 (0.96) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| Methyleugenol SCHEMBL27600712 | 0.86 | ALDH1A1 (0.96) | ALDH1A1PPARAPPARGPPARDPTGS1 | |
| SCHEMBL22922687 | 0.85 | ALDH1A1 (0.65) | ALDH1A1PPARAPPARGPPARDPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-9125406-B2 | Methods and compositions for control of cabbage looper, trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | disclosed |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | SIMON FRASER UNIVERSITY (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | CDV3, ETV1, BOLA2; BOLA2B | ALDH1A1 2318/4885PPARA 2699/4885PPARG 3571/4885 |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | ALDH1A1 4074/4885PPARA 3865/4885PPARG 4433/4885 |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | ALDH1A1 4132/4885PPARA 3859/4885PPARG 4431/4885 |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | CDV3, ETV1, TMSB4X | ALDH1A1 2444/4885PPARA 2751/4885PPARG 3507/4885 |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | L3MBTL3, L3MBTL4, L3MBTL1 | ALDH1A1 4180/4885PPARA 3912/4885PPARG 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.