SCHEMBL28465322

SCHEMBL28465322

Nc1ccc(Cl)cc1P(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
CYP3A4 P08684 3/20 0.48
ALDH1A1 P00352 3/20 0.48
ALOX15 P16050 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPGD P15428 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TP53 P04637 1/20 0.41
RECQL P46063 1/20 0.41
FADS1 O60427 1/20 0.40
ABL1 P00519 1/20 0.38
GCK P35557 1/20 0.37
GGPS1 O95749 1/20 0.37
CA1 P00915 1/20 0.37
CA14 Q9ULX7 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28466278 0.96 TSHR (0.45) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2
SCHEMBL10800047 0.83 ALDH1A1 (0.48) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2
SCHEMBL24073774 0.79 CYP3A4 (0.48) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2
SCHEMBL4350656 0.78 TSHR (0.44) TSHRCYP3A4ALDH1A1SMN1; SMN2TDP1
SCHEMBL1708793 0.78 TDP1 (0.42) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2
SCHEMBL31236948 0.77 CA2 (0.39) ALDH1A1ALOX15TDP1KDM4E
SCHEMBL8772914 0.77 CA2 (0.39) ALDH1A1ALOX15TDP1KDM4E
SCHEMBL17607326 0.75 ALOX15 (0.48) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2
SCHEMBL14601681 0.75 KDM4E (0.47) ALDH1A1ALOX15MAPK1CA1CA14
SCHEMBL29633722 0.75 ALOX15 (0.48) TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111849193-A Preparation method of modified pigment red 57:1 江苏丽王科技股份有限公司 2020-10-30 CN claimed
CN-111849193-A Preparation method of modified pigment red 57:1 江苏丽王科技股份有限公司 2020-10-30 CN disclosed