Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730372 | 1.00 | TSHR (0.47) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL2838449 | 0.95 | TSHR (0.49) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL1901317 | 0.89 | TSHR (0.52) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL2594005 | 0.89 | TSHR (0.52) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL60716 | 0.88 | TSHR (0.45) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL10909680 | 0.88 | TSHR (0.45) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL9791630 | 0.88 | TSHR (0.36) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL193930 | 0.85 | TSHR (0.55) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL306870 | 0.85 | TSHR (0.55) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL346928 | 0.85 | TSHR (0.55) | TSHRLMNAL3MBTL1PDE4ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3214178-B1 | POLYOL-BASED OSMOTIC POLYDIXYLITOL POLYMER BASED GENE TRANSPORTER AND USE THEREOF | SEOUL NAT UNIV R&DB FOUNDATION (KR) | 2023-10-04 | — | — | EP | disclosed |
| CN-106413666-B | Dental cement | 可乐丽则武齿科株式会社 | 2020-07-28 | — | — | CN | disclosed |
| CN-106456452-B | Self-adhesive dental composite resin | 可乐丽则武齿科株式会社 | 2020-01-31 | — | — | CN | disclosed |
| US-10123947-B2 | Dental cement | KURARAY NORITAKE DENTAL INC (JP) | 2018-11-13 | — | — | US | disclosed |
| US-10086083-B2 | Polyol-based osmotic polydixylitol polymer gene transporter and use thereof | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2018-10-02 | — | — | US | disclosed |
| US-9844495-B2 | Self-adhesive dental composite resin | KURARAY NORITAKE DENTAL INC. (JP) | 2017-12-19 | — | — | US | disclosed |
| EP-3214178-A1 | POLYOL-BASED OSMOTIC POLYDIXYLITOL POLYMER BASED GENE TRANSPORTER AND USE THEREOF | Seoul National University R&DB Foundation (KR) | 2017-09-06 | — | — | EP | disclosed |
| US-20170246309-A1 | POLYOL-BASED OSMOTIC POLYDIXYLITOL POLYMER GENE TRANSPORTER AND USE THEREOF | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2017-08-31 | — | — | US | disclosed |
| US-20170135910-A1 | SELF-ADHESIVE DENTAL COMPOSITE RESIN | KURARAY NORITAKE DENTAL INC. (JP) | 2017-05-18 | — | — | US | disclosed |
| US-20170135909-A1 | DENTAL CEMENT | KURARAY NORITAKE DENTAL INC. (JP) | 2017-05-18 | — | — | US | disclosed |
| US-20100048762-A1 | COMPOSITION AND DENTAL MATERIAL | KURARAY MEDICAL INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100036075-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | KURARAY MEDICAL INC. (JP) | 2010-02-11 | — | — | US | disclosed |
| CN-101636420-A | Polymerizable monomer, polymerizable composition and dental material | KURARAY MEDICAL INC (JP) | 2010-01-27 | — | — | CN | disclosed |
| CN-101595138-A | Polymerizable monomer-containing composition | KURARAY MEDICAL INC (JP) | 2009-12-02 | — | — | CN | disclosed |
| CN-101595139-A | Polymerizable monomer-containing composition | KURARAY MEDICAL INC (JP) | 2009-12-02 | — | — | CN | disclosed |
| CN-101589070-A | Composition and dental material | KURARAY MEDICAL INC (JP) | 2009-11-25 | — | — | CN | disclosed |
| EP-2112177-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | Kuraray Medical Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-2112178-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | Kuraray Medical Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-2108663-A1 | POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| EP-2108664-A1 | COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10123947-B2 | Dental cement | GRIN1, NR1D1, GRIA1 | TSHR 1780/4885LMNA 4432/4885L3MBTL1 3675/4885 |
| US-20170135910-A1 | SELF-ADHESIVE DENTAL COMPOSITE RESIN | ADGRF1, NR1I3, NR1D1 | TSHR 1807/4885LMNA 3994/4885L3MBTL1 3767/4885 |
| US-20100048762-A1 | COMPOSITION AND DENTAL MATERIAL | PHOSPHO1, PDS5B, ITGB5 | TSHR 4802/4885LMNA 2758/4885L3MBTL1 2923/4885 |
| US-10086083-B2 | Polyol-based osmotic polydixylitol polymer gene transporter and use thereof | SLC22A3, SLC22A12, SLC22A11 | TSHR 4065/4885LMNA 3042/4885L3MBTL1 885/4885 |
| US-20170246309-A1 | POLYOL-BASED OSMOTIC POLYDIXYLITOL POLYMER GENE TRANSPORTER AND USE THEREOF | SLC22A3, SLC22A12, SLC22A11 | TSHR 4065/4885LMNA 3042/4885L3MBTL1 885/4885 |
| US-20170135909-A1 | DENTAL CEMENT | GRIN1, NR1D1, GRIA1 | TSHR 1780/4885LMNA 4432/4885L3MBTL1 3675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.