Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846558 | 1.00 | TSHR (0.47) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL2838449 | 0.95 | TSHR (0.49) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL1901317 | 0.89 | TSHR (0.52) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL2594005 | 0.89 | TSHR (0.52) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL60716 | 0.88 | TSHR (0.45) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL10909680 | 0.88 | TSHR (0.45) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL9791630 | 0.88 | TSHR (0.36) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL193930 | 0.85 | TSHR (0.55) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL306870 | 0.85 | TSHR (0.55) | TSHRLMNAL3MBTL1PDE4ATHRB | |
| SCHEMBL346928 | 0.85 | TSHR (0.55) | TSHRLMNAL3MBTL1PDE4ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240198316-A1 | SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS | SUZHOU SEPAX TECHNOLOGIES, INC. (CN) | 2024-06-20 | — | — | US | claimed |
| EP-4337357-A1 | SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS | Suzhou Sepax Technologies, Inc. (CN) | 2024-03-20 | — | — | EP | claimed |
| CN-117377521-A | Synthetic polymeric porous media with hierarchical multi-layer structure and design, synthesis, modification and liquid chromatography applications thereof | 苏州赛分科技股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| WO-2022253175-A1 | SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS | SUZHOU SEPAX TECHNOLOGIES, INC (CN) | 2022-12-08 | — | — | WO | claimed |
| WO-2022252071-A1 | A SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS | SUZHOU SEPAX TECHNOLOGIES, INC (CN) | 2022-12-08 | — | — | WO | claimed |
| US-9138488-B2 | Polysorbitol-based osmotically active transporter and gene therapy using same | SNU R&DB FOUNDATION (KR) | 2015-09-22 | — | — | US | claimed |
| US-20140348777-A1 | Polysorbitol-Based Osmotically Active Transporter and Gene Therapy Using Same | SNU R&DB FOUNDATION (KR) | 2014-11-27 | — | — | US | claimed |
| US-8294975-B2 | Automotive rearview mirror assembly | DONNELLY CORPORATION (US) | 2012-10-23 | — | — | US | claimed |
| US-20100110523-A1 | AUTOMOTIVE REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2010-05-06 | — | — | US | claimed |
| US-7202987-B2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2007-04-10 | — | — | US | claimed |
| US-6627720-B2 | Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels | JOHNSON POLYMER, LLC | 2003-09-30 | — | — | US | claimed |
| US-6265511-B1 | BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER | S. C. JOHNSON COMMERICAL MARKETS, INC. | 2001-07-24 | — | — | US | claimed |
| US-6154306-A | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2000-11-28 | — | — | US | claimed |
| EP-0612826-B1 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices | DONNELLY CORP (US) | 2000-10-04 | — | — | EP | claimed |
| EP-1004649-A2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2000-05-31 | — | — | EP | claimed |
| US-6002511-A | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 1999-12-14 | — | — | US | claimed |
| WO-1998040425-A1 | COMPOSITE WATER SWELLABLE ELASTOMERS AND METHOD OF PREPARATION THEREOF | SULC JIRI (CZ) | 1998-09-17 | — | — | WO | claimed |
| EP-0612826-A1 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices | DONNELLY CORPORATION (US) | 1994-08-31 | — | — | EP | claimed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | claimed |
| US-4082894-A | COATING WITH PRIMER POLYMER, DRYING, CURING MELAMINE-TYPE RESIN COATING | NIPPON SHEET GLASS CO., LTD. (JA) | 1978-04-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348777-A1 | Polysorbitol-Based Osmotically Active Transporter and Gene Therapy Using Same | SLC20A1, SLC34A1, SLC26A6 | TSHR 3736/4885LMNA 1956/4885L3MBTL1 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.