SCHEMBL28465646

SCHEMBL28465646

NCC(=O)N1CCC[C@H]1C(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.44
HSD11B1 P28845 1/20 0.44
MGLL Q99685 1/20 0.44
ALDH1A1 P00352 6/20 0.43
LMNA P02545 2/20 0.43
DPP4 P27487 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
DPP9 Q86TI2 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
TSHR P16473 1/20 0.41
SLC18A3 Q16572 1/20 0.41
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28465649 1.00 HTR2A (0.44) HTR2AHSD11B1MGLLALDH1A1LMNA
SCHEMBL4372293 0.83 ALDH1A1 (0.41) ALDH1A1DPP4DPP8DPP9DPP7
Glycyl Proline SCHEMBL28119301 0.83 ALDH1A1 (0.43) ALDH1A1LMNADPP4DPP8DPP9
SCHEMBL18509855 0.82 NAMPT (0.53) ALDH1A1LMNAKMT2AMEN1MMP2
SCHEMBL30119875 0.82 CYP1A2 (0.46) MGLLALDH1A1LMNADPP4DPP8
SCHEMBL4372297 0.82 NAMPT (0.53) ALDH1A1LMNAKMT2AMEN1MMP2
SCHEMBL379486 0.82 NAMPT (0.53) ALDH1A1LMNAKMT2AMEN1MMP2
Bromide SCHEMBL11455325 0.81 NAMPT (0.52) ALDH1A1LMNAKMT2AMEN1MMP2
Hydrochloric Acid SCHEMBL5087159 0.81 NAMPT (0.52) ALDH1A1LMNAKMT2AMEN1MMP2
Hydrochloric Acid SCHEMBL20214289 0.81 NAMPT (0.52) ALDH1A1LMNAKMT2AMEN1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111778312-B Kit for determining glycylproline dipeptidyl aminopeptidase in serum 迪瑞医疗科技股份有限公司 2023-05-12 CN claimed
CN-111778312-A Kit for determining glycylproline dipeptide aminopeptidase in serum 迪瑞医疗科技股份有限公司 2020-10-16 CN claimed
CN-119242502-A Lactobacillus paracasei 1A74 and application thereof in reducing blood glucose 广西皇氏乳业有限公司 2025-01-03 CN disclosed
CN-114292766-B Lactobacillus gasseri with blood glucose reducing capability and application thereof 卡士乳业(深圳)有限公司 2024-04-19 CN disclosed
CN-111778312-B Kit for determining glycylproline dipeptidyl aminopeptidase in serum 迪瑞医疗科技股份有限公司 2023-05-12 CN disclosed
CN-114292766-A Lactobacillus gasseri with blood glucose reducing capability and application thereof 卡士乳业(深圳)有限公司 2022-04-08 CN disclosed
CN-111778312-A Kit for determining glycylproline dipeptide aminopeptidase in serum 迪瑞医疗科技股份有限公司 2020-10-16 CN disclosed