SCHEMBL379486

SCHEMBL379486

NCC(=O)N1CCC[C@H]1C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.53
LMNA P02545 3/20 0.52
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
ALDH1A1 P00352 4/20 0.48
GAA P10253 1/20 0.47
HTT P42858 2/20 0.46
EPHX2 P34913 1/20 0.46
NPC1 O15118 1/20 0.46
KMT2A Q03164 2/20 0.45
EPHX1 P07099 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
PABPC1 P11940 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18509855 1.00 NAMPT (0.53) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL4372297 1.00 NAMPT (0.53) NAMPTLMNAMMP2MMP9ALDH1A1
Hydrochloric Acid SCHEMBL5087159 0.99 NAMPT (0.52) NAMPTLMNAMMP2MMP9ALDH1A1
Bromide SCHEMBL11455325 0.99 NAMPT (0.52) NAMPTLMNAMMP2MMP9ALDH1A1
Hydrochloric Acid SCHEMBL20214289 0.99 NAMPT (0.52) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL4953664 0.96 NAMPT (0.49) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL4953654 0.96 NAMPT (0.49) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL5172065 0.89 F2 (0.51) NAMPTLMNAMMP2MMP9ALDH1A1
Glycyl Proline SCHEMBL28466633 0.86 F2 (0.48) LMNAMMP2MMP9ALDH1A1EPHX2
SCHEMBL28579566 0.86 LMNA (0.48) LMNAMMP2MMP9ALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118256579-A Preparation method of salmon skin DPP-IV inhibitory peptide 集美大学 2024-06-28 CN claimed
CN-117886883-A Thin-shell source peptide LTWR and preparation method and application thereof 广西大学 2024-04-16 CN claimed
WO-2022180415-A1 METHODS FOR PREDICTION OF SEVERITY AND RISK OF MORTALITY OF COVID-19 DISEASE AND PRE-SCREENING OF ACUTE SARS-COV-2 INFECTIONS RAMGEN ZÁRTKÖRŰEN MŰKÖDŐ RÉSZVÉNYTÁRSASÁG (HU) 2022-09-01 WO claimed
EP-1221954-B1 METHODS FOR IDENTIFYING INHIBITORS OF METHIONINE AMINOPEPTIDASES UNIV SAINT LOUIS (US) 2006-09-13 EP claimed
US-20030180828-A1 Biological markers and diagnostic tests for angiotensin converting enzyme inhibitor-and vasopeptidase inhibitor-associated angioedema NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-09-25 US claimed
US-20020137120-A1 Biological markers and diagnostic tests for angiotensin converting enzyme inhibitor-and vasopeptidase inhibitor-associated angioedema VANDERBILT UNIVERSITY 2002-09-26 US claimed
US-4191808-A DIPEPTIDE CONTAINING PROLINE AND A PHOTOMETRICALLY DETECTABLE NITROANILINE, PHENYLAZOANILINE OR PHENYLAZONAPHTHYLAMINE GROUP AJINOMOTO CO., INC. (JP) 1980-03-04 US claimed
WO-2026103814-A1 IRREVERSIBLE FAP INHIBITOR AND USE THEREOF 南京科络思生物科技有限公司 2026-05-21 WO disclosed
US-20260137820-A1 TRIFUNCTIONAL COMPOUND AND USE THEREOF PEKING UNIV (CN) 2026-05-21 US disclosed
CN-117903243-B Fructus cannabis extract polypeptide and application thereof 清华大学深圳国际研究生院 2026-05-12 CN disclosed
US-20260014245-A1 NEW MERS-COV VACCINE MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN HELMHOLTZ GEMEINSCHAFT (DE) 2026-01-15 US disclosed
CN-119661645-B Sea cucumber protein heptapeptide with blood pressure and blood sugar reducing functions and application thereof 山东栖蔓生物科技有限公司 2025-05-27 CN disclosed
CN-120025403-A Novel ACE (angiotensin converting enzyme) inhibitory peptide with DPP-IV inhibitory activity and application thereof 威海迪普森生物科技有限公司 2025-05-23 CN disclosed
WO-1996038550-A1 A NOVEL FORM OF DIPEPTIDYLPEPTIDASE IV (CD26) FOUND IN HUMAN SERUM, ANTIBODIES THERETO, AND USES THEREFOR DANA-FARBER CANCER INSTITUTE, INC. (US) 1996-12-05 WO disclosed
WO-1994028915-A1 HIV RETROVIRUS INFECTION INHIBITOR CAPABLE OF INTERACTING WITH CD26 RECEPTOR INSTITUT PASTEUR (FR) 1994-12-22 WO disclosed
WO-1993007872-A1 LYSOSOMAL ENZYME INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES THE UNIVERSITY OF NOTTINGHAM (GB) 1993-04-29 WO disclosed
US-RE33635-E Enzymatic assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1991-07-09 US disclosed
US-4681841-A CONSUMING OXYGEN OR GENERATING A PIGMENT; MEASUREMENT BY AN OXYGEN ELECTRODE OR COLORIMETRIC ASSAY TOYO JOZO KABUSHIKI KAISHA (JP) 1987-07-21 US disclosed
US-4191808-A DIPEPTIDE CONTAINING PROLINE AND A PHOTOMETRICALLY DETECTABLE NITROANILINE, PHENYLAZOANILINE OR PHENYLAZONAPHTHYLAMINE GROUP AJINOMOTO CO., INC. (JP) 1980-03-04 US disclosed
US-4119620-A Novel dipeptide derivatives, salts thereof, and method of measuring enzyme activity AJINOMOTO CO., INC. (JP) 1978-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137820-A1 TRIFUNCTIONAL COMPOUND AND USE THEREOF STAU1, TIA1, GAR1 NAMPT 3738/4885LMNA 730/4885MMP2 3791/4885
US-20260014245-A1 NEW MERS-COV VACCINE TMPRSS4, DPP4, TMPRSS2 NAMPT 1067/4885LMNA 1742/4885MMP2 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.