Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5087159

Cl.NCC(=O)N1CCC[C@H]1C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA known ✓ P10253 1/20 0.46
NAMPT P43490 1/20 0.52
LMNA P02545 3/20 0.51
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
ALDH1A1 P00352 4/20 0.47
HTT P42858 2/20 0.46
KDM1A O60341 1/20 0.46
RCOR1 Q9UKL0 1/20 0.46
EPHX2 P34913 1/20 0.45
NPC1 O15118 1/20 0.45
KMT2A Q03164 2/20 0.44
EPHX1 P07099 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
PABPC1 P11940 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20214289 1.00 NAMPT (0.52) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL18509855 0.99 NAMPT (0.53) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL379486 0.99 NAMPT (0.53) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL4372297 0.99 NAMPT (0.53) NAMPTLMNAMMP2MMP9ALDH1A1
Bromide SCHEMBL11455325 0.98 NAMPT (0.52) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL4953654 0.95 NAMPT (0.49) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL4953664 0.95 NAMPT (0.49) NAMPTLMNAMMP2MMP9ALDH1A1
SCHEMBL5172065 0.88 F2 (0.51) NAMPTLMNAMMP2MMP9ALDH1A1
Glycyl Proline SCHEMBL28466633 0.85 F2 (0.48) LMNAMMP2MMP9ALDH1A1EPHX2
SCHEMBL28579566 0.85 LMNA (0.48) LMNAMMP2MMP9ALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12575589-B2 Chia seed derived products and the process thereof PURDUE RESEARCH FOUNDATION (US) 2026-03-17 US disclosed
EP-4698629-A1 DERIVATION OF PRIMARY EPITHELIAL ORGANOIDS UCL Business Ltd (GB) 2026-02-25 EP disclosed
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP disclosed
CN-119019492-B Spirulina source natural DPP-IV inhibitory peptide and preparation method and application thereof 中国科学院烟台海岸带研究所 2025-01-28 CN disclosed
US-20240415155-A1 CHIA SEED DERIVED PRODUCTS AND THE PROCESS THEREOF PURDUE RESEARCH FOUNDATION (US) 2024-12-19 US disclosed
CN-119019492-A Spirulina source natural DPP-IV inhibitory peptide and preparation method and application thereof 中国科学院烟台海岸带研究所 2024-11-26 CN disclosed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US disclosed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO disclosed
WO-2024218496-A1 DERIVATION OF PRIMARY EPITHELIAL ORGANOIDS UCL BUSINESS LTD (GB) 2024-10-24 WO disclosed
CN-118599817-A Recombinant DPP4 and preparation method thereof, DNA fragment, recombinant vector, recombinant cell and recombinant escherichia coli 深圳大学 2024-09-06 CN disclosed
US-11805795-B2 Chia seed derived products and the process thereof PURDUE RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
CN-116790434-A Lactobacillus pentosus and application thereof in preparation of sugar metabolism regulator 中国海洋大学 2023-09-22 CN disclosed
CN-113425747-A Application of bacillus coagulans JA845 in preparation of enzyme activity inhibitor with hypoglycemic function 吉林省农业科学院 2021-09-24 CN disclosed
CN-108048489-B Method for preparing DPP-IV inhibitor by using Paenibacillus polymyxa and prepared DPP-IV inhibitor 光明乳业股份有限公司 2021-09-07 CN disclosed
EP-3107556-B1 COMPOSITIONS FOR PREVENTING AND/OR TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH ALPHA-GLUCOSIDASE UNIV LA ROCHELLE (FR) 2019-04-10 EP disclosed
US-20180104303-A1 COMPOSITIONS FOR PREVENTING AND/OR TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH ALPHA-GLUCOSIDASE UNIVERSITE CLERMONT AUVERGNE (FR) 2018-04-19 US disclosed
EP-3107556-A1 COMPOSITIONS FOR PREVENTING AND/OR TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH ALPHA-GLUCOSIDASE Universite De La Rochelle (FR) 2016-12-28 EP disclosed
WO-2015124867-A1 COMPOSITIONS FOR PREVENTING AND/OR TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH ALPHA-GLUCOSIDASE Université de la Rochelle (FR) 2015-08-27 WO disclosed
US-20080050460-A1 Uses of lectin-conotoxin SAVIDGE TOR C 2008-02-28 US disclosed
WO-2007146185-A2 USES OF LECTIN-CONOTOXIN SAVIDGE TOR C (US) 2007-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12575589-B2 Chia seed derived products and the process thereof CHIA, CHI3L1, CHI3L2 GAA 164/4885NAMPT 3516/4885LMNA 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.