SCHEMBL2846730

SCHEMBL2846730

CC(=O)OCC1(COC(C)=O)COC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 4/20 0.36
EPHX1 P07099 1/20 0.36
PRKCA P17252 3/20 0.34
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3462874 0.90 TSHR (0.46) ALDH1A1LMNAHSD17B10TSHREPHX1
SCHEMBL9838034 0.90 EPHX1 (0.41) ALDH1A1LMNAHSD17B10TSHREPHX1
SCHEMBL31437395 0.88 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10TSHREPHX1
SCHEMBL13822823 0.80 PRKCA (0.44) ALDH1A1PRKCA
SCHEMBL3462902 0.80 EPHX1 (0.44) ALDH1A1LMNAHSD17B10TSHREPHX1
SCHEMBL8448704 0.78 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHRPRKCA
SCHEMBL18134200 0.78 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHRPRKCA
SCHEMBL31341749 0.77 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10PRKCASMN1; SMN2
SCHEMBL18786112 0.75 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10PRKCA
SCHEMBL10349285 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090088506-A1 SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING BOTH POLYOXIRANE AND POLYOXETANE BLOCKS ALLIANT TECHSYSTEMS INC. (US) 2009-04-02 US claimed
US-20080121845-A1 Oxetane composition, associated method and article GENERAL ELECTRIC COMPANY (US) 2008-05-29 US claimed
WO-2008021139-A1 OXETANE COMPOSITION, ASSOCIATED METHOD AND ARTICLE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-02-21 WO claimed
US-20080039608-A1 Oxetane composition, associated method and article GENERAL ELECTRIC COMPANY (US) 2008-02-14 US claimed
WO-2008019149-A1 COMPOSITION AND ASSOCIATED METHOD MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-02-14 WO claimed
US-20080039542-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2008-02-14 US claimed
WO-2008019151-A1 OXETANE COMPOSITION, ASSOCIATED METHOD AND ARTICLE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-02-14 WO claimed
US-7101955-B1 Synthesis of energetic thermoplastic elastomers containing both polyoxirane and polyoxetane blocks ALLIANT TECHSYSTEMS INC. (US) 2006-09-05 US claimed
US-6815522-B1 BINDER IN SOLID STATE AT ROOM TEMPERATURE HAVING A BLOCKS AND B BLOCKS CONNECTED VIA LINKING GROUPS DERIVED FROM URETHANE OLIGOMER DIOL; A BLOCKS ARE CRYSTALLINE BELOW ABOUT 60 DEGREES C.; B BLOCKS ARE AMORPHOUS ABOVE ABOUT -20 DEGREES C. ALLIANT TECHSYSTEMS INC. 2004-11-09 US claimed
EP-1144473-B1 SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING BOTH POLYOXIRANE AND POLYOXETANE BLOCKS ALLIANT TECHSYSTEMS INC (US) 2003-09-24 EP claimed
EP-1141062-B1 SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING OLIGOMERIC URETHANE LINKAGES ALLIANT TECHSYSTEMS INC (US) 2003-02-12 EP claimed
EP-0335499-B1 Method of producing thermoplastic elastomers having alternate crystalline structure for use as binders in high-energy compositions THIOKOL CORP (US) 1998-07-15 EP claimed
US-5516854-A BLOCK POLYMERIZATION TO FORM POLYETHERS THAT CAN BE ENDCAPPED WITH URETHANE GROUPS THIOKOL CORPORATION (US) 1996-05-14 US claimed
EP-0335499-A2 Method of producing thermoplastic elastomers having alternate crystalline structure for use as binders in high-energy compositions THIOKOL CORPORATION (US) 1989-10-04 EP claimed
EP-4743503-A1 DUAL CURABLE OLIGOMERS ARKEMA France (FR) 2026-05-20 EP disclosed
EP-4642646-A1 SULFONIUM SALT PHOTOINITIATORS AND METHODS OF LED CURING A COMPOSITION WITH SAID SULFONIUM SALT PHOTOINITIATORS ARKEMA France (FR) 2025-11-05 EP disclosed
EP-4642770-A1 TRIARYLSULFONIUM BASED PHOTOINITIATORS FOR LED CURE OF CATIONIC, FREE RADICAL AND HYBRID CATIONIC/FREE RADICAL FORMULATIONS ARKEMA France (FR) 2025-11-05 EP disclosed
US-4952644-A Synthesis of ABA triblock polymers and An B star polymers from cyclic ethers THIOKOL CORPORATION (US) 1990-08-28 US disclosed
EP-0335499-A2 Method of producing thermoplastic elastomers having alternate crystalline structure for use as binders in high-energy compositions THIOKOL CORPORATION (US) 1989-10-04 EP disclosed
US-4806613-A ENCAPPING WITH DIISOCYANATE; COUPLING MORTON THIOKOL, INC. (US) 1989-02-21 US disclosed