Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134200 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL30683844 | 0.90 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL7195368 | 0.88 | LMNA (0.39) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL14681226 | 0.88 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL5648942 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL28826436 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL15725846 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL24920444 | 0.83 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10GAAGALR3 | |
| SCHEMBL5645134 | 0.81 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10GAASMN1; SMN2 | |
| SCHEMBL31196271 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10GALR3PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190275180-A1 | HYPERPOLARIZED 1-13C-1,1-BIS(ACETOXY(METHYL))-2,2'-CYCLOPROPANE AS METABOLIC MARKER FOR MR | BRACCO IMAGING S.P.A. (IT) | 2019-09-12 | — | — | US | disclosed |
| US-7271268-B1 | Process for preparation of [1-(mercaptomethyl)cyclopropyl]acetic acid and related derivatives | FORMOSA LABORATORIES INC. (TW) | 2007-09-18 | — | — | US | disclosed |
| US-7271268-B1 | Process for preparation of [1-(mercaptomethyl)cyclopropyl]acetic acid and related derivatives | FORMOSA LABORATORIES INC. (TW) | 2007-09-18 | — | — | US | disclosed |
| EP-0502690-B1 | Cyclopropane derivative | AJINOMOTO KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0502690-A2 | Cyclopropane derivative | Ajinomoto Co., Inc. (JP) | 1992-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190275180-A1 | HYPERPOLARIZED 1-13C-1,1-BIS(ACETOXY(METHYL))-2,2'-CYCLOPROPANE AS METABOLIC MARKER FOR MR | CYP11B1, CYC1, CYP11B2 | ALDH1A1 801/4885LMNA 2737/4885HSD17B10 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.