Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526096 | 0.92 | TLR8 (0.54) | TLR8CNR2HRH2HRH1ACKR3 | |
| SCHEMBL106768 | 0.92 | TLR8 (0.54) | TLR8CNR2HRH2HRH1ACKR3 | |
| SCHEMBL29129466 | 0.90 | TLR8 (0.53) | TLR8CNR2HRH2HRH1ACKR3 | |
| SCHEMBL4543892 | 0.87 | TLR8 (0.55) | TLR8CNR2ACKR3CHRM2CHRM4 | |
| SCHEMBL8253901 | 0.84 | USP2 (0.51) | TLR8ACKR3CHRM2CHRM4CHRM1 | |
| SCHEMBL20873847 | 0.82 | USP2 (0.53) | TLR8ACKR3CHRM2CHRM4CHRM1 | |
| 2-Aminopyridine SCHEMBL28568460 | 0.81 | TLR8 (0.50) | TLR8CNR2HRH2HRH1ACKR3 | |
| SCHEMBL29165973 | 0.81 | GPR119 (0.46) | TLR8CNR2HRH2HRH1ACKR3 | |
| SCHEMBL2616174 | 0.81 | USP2 (0.51) | TLR8ACKR3CHRM2CHRM4CHRM1 | |
| SCHEMBL27097882 | 0.81 | TLR8 (0.50) | TLR8HRH2HRH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-B | Tripeptide epoxy ketone compound constructed by heterocycle, preparation and application | 浙江大学 | 2020-08-11 | — | — | CN | disclosed |