Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721209 | 0.87 | TRPV1 (0.69) | ALDH1A1TSHRGAANFKB1TRPV1 | |
| SCHEMBL5707095 | 0.87 | MTNR1A (0.69) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL2936661 | 0.87 | ALDH1A1 (0.78) | ALDH1A1TDP1MEN1POLBKMT2A | |
| SCHEMBL4208734 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL27591942 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL2846746 | 0.85 | TRPV1 (0.69) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL8168115 | 0.84 | ALDH1A1 (0.67) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL6418730 | 0.84 | MTNR1A (0.66) | ALDH1A1TSHRGAANFKB1TDP1 | |
| SCHEMBL17205705 | 0.84 | CYP1A2 (0.71) | ALDH1A1TSHRTRPV1CYP1A2CYP3A4 | |
| SCHEMBL5681720 | 0.84 | ERCC1 (0.69) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11946083-B2 | Method for the microbial production of specific natural capsaicinoids | CONAGEN INC. (US) | 2024-04-02 | — | — | US | claimed |
| CN-112608247-B | Preparation method of capsaicin and capsaicin prepared by using same | 遂宁晶安科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| US-20220403427-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | CONAGEN INC. (US) | 2022-12-22 | — | — | US | claimed |
| EP-3946317-A1 | COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL | Mestex AG (CH) | 2022-02-09 | — | — | EP | claimed |
| US-20220008384-A1 | COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL | MESTEX AG (CH) | 2022-01-13 | — | — | US | claimed |
| US-20210317485-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | CONAGEN INC. | 2021-10-14 | — | — | US | claimed |
| CN-112608247-A | Preparation method of capsaicin and capsaicin prepared by using same | 遂宁晶安科技有限公司 | 2021-04-06 | — | — | CN | claimed |
| WO-2020191506-A1 | COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL | MESTEX AG (CH) | 2020-10-01 | — | — | WO | claimed |
| EP-3487986-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | Conagen Inc. (US) | 2019-05-29 | — | — | EP | claimed |
| WO-2018017772-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | CONAGEN INC. (US) | 2018-01-25 | — | — | WO | claimed |
| EP-1827405-A2 | CAPSAICINOID GEL FORMULATION AND USES THEREOF | Algorx Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| US-20070036876-A1 | Relieving pain at a body site by administering a dosage of capsaicinoid at the painful site without eliciting an effect outside the discrete location; local anesthetic effect; targeted therapy | ALGORX (US) | 2007-02-15 | — | — | US | claimed |
| US-20060269628-A1 | Infiltration of capsaicin into surgical sites and open wounds | ALGORX (US) | 2006-11-30 | — | — | US | claimed |
| US-20060148903-A1 | Capsaicinoid gel formulation and uses thereof | ALGORX PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | US | claimed |
| WO-2006058140-A2 | CAPSAICINOID GEL FORMULATION AND USES THEREOF | ALGORX PHARMACEUTICALS, INC. (US) | 2006-06-01 | — | — | WO | claimed |
| JP-2006513267-A | — | — | 2006-04-20 | — | — | JP | claimed |
| EP-1605956-A1 | ADMINISTRATION OF CAPSAICINOIDS | Algorx Pharmaceuticals, Inc. (US) | 2005-12-21 | — | — | EP | claimed |
| US-20050020690-A1 | Infiltration of capsaicin into surgical sites and open wounds | ALGORX (US) | 2005-01-27 | — | — | US | claimed |
| US-20050019436-A1 | Injectable capsaicin | ALGORX (US) | 2005-01-27 | — | — | US | claimed |
| WO-2004058286-A1 | ADMINISTRATION OF CAPSAICINOIDS | ALGORX PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317485-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | TRPV1, CYP51A1, NAAA | ALDH1A1 1564/4885TSHR 4590/4885GAA 1127/4885 |
| US-20220403427-A1 | METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS | TRPV1, CYP51A1, NAAA | ALDH1A1 1564/4885TSHR 4590/4885GAA 1127/4885 |
| US-11946083-B2 | Method for the microbial production of specific natural capsaicinoids | TRPV1, CYP51A1, NAAA | ALDH1A1 1564/4885TSHR 4590/4885GAA 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.