Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833247 | 0.92 | TAAR1 (0.62) | GAAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9416518 | 0.85 | TSHR (0.58) | TRPV1ALOX15KMT2ATSHRNFKB1 | |
| SCHEMBL2846746 | 0.85 | TRPV1 (0.69) | GAAATMTRPV1PTPN7DUSP3 | |
| SCHEMBL30884017 | 0.85 | PTPN7 (0.69) | TRPV1PTPN7DUSP3 | |
| SCHEMBL2849365 | 0.85 | PTPN7 (0.69) | TRPV1PTPN7DUSP3 | |
| SCHEMBL7768865 | 0.85 | FOS (0.62) | GAAALDH1A1KDM4EPOLBALOX15 | |
| SCHEMBL3042373 | 0.85 | LMNA (0.69) | ALDH1A1KDM4EPOLBMAPTHPGD | |
| SCHEMBL23216976 | 0.84 | KMT2A (0.57) | GAAATMTRPV1ALDH1A1KDM4E | |
| SCHEMBL11856806 | 0.83 | TAAR1 (0.57) | GAAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL16057469 | 0.83 | GAA (0.64) | GAAATMTRPV1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435565-A | ENZYME INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1984-03-06 | — | — | US | disclosed |
| US-4359473-A | α-Amino deoxy clavulanic acid antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1982-11-16 | — | — | US | disclosed |