Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.53 |
| ▸ | ATP4A | P20648 | 2/20 | 0.52 |
| ▸ | ATP4B | P51164 | 2/20 | 0.52 |
| ▸ | DHODH | Q02127 | 7/20 | 0.51 |
| ▸ | EIF4E | P06730 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660568 | 0.86 | ATP4A (0.58) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL14098391 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL25276567 | 0.81 | PKM (0.56) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL31401007 | 0.81 | MPL (0.58) | SMN1; SMN2NPC1RAB9AKDM4EGSTO1 | |
| SCHEMBL27751529 | 0.80 | ATP4A (0.58) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL13484523 | 0.79 | DHODH (0.58) | SMN1; SMN2NPC1RAB9AKDM4EGSTO1 | |
| SCHEMBL7434486 | 0.78 | ATP4A (0.50) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL167820 | 0.78 | RAB9A (0.58) | SMN1; SMN2NPC1RAB9AKDM4EGSTO1 | |
| SCHEMBL167409 | 0.77 | HPGDS (0.60) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL7434493 | 0.77 | ATP4A (0.59) | SMN1; SMN2NPC1RAB9AKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875559-B | Thiazole hydrazide derivatives and application thereof as agricultural bactericide | 南京农业大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-111875559-A | Thiazole hydrazide derivatives and application thereof as agricultural bactericide | 南京农业大学 | 2020-11-03 | — | — | CN | disclosed |