Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.62 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395810 | 0.89 | OPRD1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL16570950 | 0.89 | OPRD1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL30620560 | 0.89 | OPRD1 (0.66) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL28470432 | 0.89 | OPRD1 (0.63) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL10243104 | 0.86 | OPRM1 (0.65) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082393 | 0.85 | OPRD1 (0.74) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082084 | 0.83 | OPRD1 (0.76) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL15501040 | 0.83 | OPRD1 (0.73) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL29416620 | 0.82 | OPRD1 (0.78) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL547917 | 0.82 | OPRD1 (0.78) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727444-B | Synthesis method of morphine-6-beta-D-glucuronide and intermediate compound thereof | 宜昌人福药业有限责任公司 | 2020-10-23 | — | — | CN | disclosed |