SCHEMBL16570950

SCHEMBL16570950

CN1CC[C@]23c4c5ccc(Oc6ccc([N+](=O)[O-])cc6[N+](=O)[O-])c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 8/20 0.66
▸ OPRM1 P35372 7/20 0.66
▸ OPRK1 P41145 5/20 0.66
▸ MRGPRX2 Q96LB1 4/20 0.66
▸ ADRB1 P08588 1/20 0.66
▸ PDE4D Q08499 1/20 0.66
▸ PDE3A Q14432 1/20 0.66
▸ SLC22A1 O15245 1/20 0.59
▸ ADRA2A P08913 1/20 0.59
▸ ARRB1 P49407 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395810 1.00 OPRD1 (0.66) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL30620560 1.00 OPRD1 (0.66) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL28468334 0.89 OPRM1 (0.62) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL29416620 0.85 OPRD1 (0.78) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL547917 0.85 OPRD1 (0.78) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL28470432 0.84 OPRD1 (0.63) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL10243104 0.84 OPRM1 (0.65) OPRD1OPRM1OPRK1MRGPRX2ADRB1
Codeine SCHEMBL3475523 0.83 OPRD1 (0.88) OPRD1OPRM1OPRK1MRGPRX2ADRB1
Morphine SCHEMBL28712434 0.83 OPRD1 (0.78) OPRD1OPRM1OPRK1MRGPRX2SLC22A1
Codeine SCHEMBL4730550 0.82 OPRD1 (0.72) OPRD1OPRM1OPRK1MRGPRX2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240165022-A1 Pharmaceutical Formulation KLARIA PHARMA HOLDING AB (SE) 2024-05-23 — — US claimed
US-11904049-B2 Pharmaceutical formulation KLARIA PHARMA HOLDING AB (SE) 2024-02-20 — — US claimed
US-20230063876-A1 Virus-Like Particle Vaccines for Opioid Drugs THE REGENTS OF THE UNIVERSITY OF NEW MEXICO 2023-03-02 — — US claimed
US-20220160618-A1 Pharmaceutical Formulation KLARIA PHARMA HOLDING AB (SE) 2022-05-26 — — US claimed
US-11219600-B2 Pharmaceutical formulation KLARIA PHARMA HOLDING AB (SE) 2022-01-11 — — US claimed
EP-3932399-A1 PHARMACEUTICAL FORMULATION Klaria Pharma Holding AB (SE) 2022-01-05 — — EP claimed
EP-3634377-B1 PHARMACEUTICAL FORMULATION KLARIA PHARMA HOLDING AB (SE) 2021-07-21 — — EP claimed
US-20200246253-A1 PHARMACEUTICAL FORMULATION KLARIA PHARMA HOLDING AB (SE) 2020-08-06 — — US claimed
EP-3634377-A1 PHARMACEUTICAL FORMULATION Klaria Pharma Holding AB (SE) 2020-04-15 — — EP claimed
CN-110831575-A Pharmaceutical preparation 卡里亚制药控股有限公司 2020-02-21 — — CN claimed
EP-3560484-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2019-10-30 — — EP claimed
EP-3423034-B1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G L PHARMA GMBH (AT) 2019-07-10 — — EP claimed
WO-2018224674-A9 PHARMACEUTICAL FORMULATION KLARIA PHARMA HOLDING AB (SE) 2019-03-21 — — WO claimed
WO-2018224674-A1 PHARMACEUTICAL FORMULATION KLARIA PHARMA HOLDING AB (SE) 2018-12-13 — — WO claimed
EP-3210596-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2017-08-30 — — EP claimed
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2026-05-21 — — US disclosed
US-20260137670-A1 SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND RELATED METHODS DURECT CORP (US) 2026-05-21 — — US disclosed
US-20150098983-A1 Methods and Compositions for Treating Withdrawal Syndromes Using Non-Sedative Dexmedetomidine Transdermal Compositions TEIKOKU PHARMA USA, INC. 2015-04-09 — — US disclosed
WO-2015036734-A1 SYNERGISTIC COMBINATION OF ANALGESIC DRUGS UCL BUSINESS PLC (GB) 2015-03-19 — — WO disclosed
CN-204147375-U Be designed for the aerosol generation equipment producing condensation aerosol NICOTINE TECHNOLOGY INC E 2015-02-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246253-A1 PHARMACEUTICAL FORMULATION OGFR, OPRL1, OPRM1 OPRD1 5/4885OPRM1 3/4885OPRK1 4/4885
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ADRA2B, ADRB1, ADRB2 OPRD1 4/4885OPRM1 6/4885OPRK1 7/4885
US-20260137670-A1 SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND RELATED METHODS SLC10A2, OPRK1, HBB OPRD1 63/4885OPRM1 5/4885OPRK1 2/4885
US-20150098983-A1 Methods and Compositions for Treating Withdrawal Syndromes Using Non-Sedative Dexmedetomidine Transdermal Compositions CRH, OPRD1, ADRA2C OPRD1 2/4885OPRM1 44/4885OPRK1 4/4885
US-11219600-B2 Pharmaceutical formulation OGFR, OPRL1, OPRM1 OPRD1 5/4885OPRM1 3/4885OPRK1 4/4885
US-20220160618-A1 Pharmaceutical Formulation OGFR, OPRL1, OPRM1 OPRD1 5/4885OPRM1 3/4885OPRK1 4/4885
US-11904049-B2 Pharmaceutical formulation OGFR, OPRL1, OPRM1 OPRD1 5/4885OPRM1 3/4885OPRK1 4/4885
US-20240165022-A1 Pharmaceutical Formulation OGFR, OPRL1, OPRM1 OPRD1 5/4885OPRM1 3/4885OPRK1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback