Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutanol SCHEMBL7067169 | 0.88 | TSHR (0.50) | LMNAEGLN1TSHRALKBH5SUCNR1 | |
| Isobutanol SCHEMBL27494208 | 0.86 | TSHR (0.63) | LMNATSHROR51E2SLC22A6NFKB1 | |
| Butyric Acid SCHEMBL8159821 | 0.86 | FFAR3 (0.68) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Isobutanol SCHEMBL28242003 | 0.86 | TSHR (0.63) | LMNATSHROR51E2SLC22A6NFKB1 | |
| Succinic Acid SCHEMBL18691126 | 0.85 | LMNA (0.53) | LMNAEGLN1TSHRALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL29364481 | 0.85 | TDP1 (0.59) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1134610 | 0.85 | TDP1 (0.59) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Mercaptopropionic Acid SCHEMBL16738048 | 0.84 | ACE (0.48) | LMNAEGLN1TSHRALKBH5SUCNR1 | |
| Isobutanol SCHEMBL5570205 | 0.84 | GABRP (0.52) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Succinic Acid SCHEMBL8397315 | 0.83 | EGLN1 (0.69) | LMNAEGLN1TSHRALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112111218-A | Environment-friendly latex paint and preparation method thereof | 张可新 | 2020-12-22 | — | — | CN | disclosed |
| CN-109055026-B | Maintenance cleaning agent and maintenance cleaning method for selective wave-soldering nozzle | 广州华望汽车电子有限公司 | 2020-10-23 | — | — | CN | disclosed |