Isobutanol

Isobutanol

SCHEMBL28242003

CC(C)CO.O=C(O)CCCCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.63
LMNA P02545 2/20 0.63
NFKB1 P19838 1/20 0.63
PMP22 Q01453 1/20 0.63
GPR84 Q9NQS5 8/20 0.59
FFAR1 O14842 2/20 0.59
FFAR4 Q5NUL3 2/20 0.59
PPARG P37231 7/20 0.56
PPARD Q03181 7/20 0.56
PPARA Q07869 7/20 0.56
HDAC11 Q96DB2 5/20 0.56
PTPN1 P18031 3/20 0.56
ALDH1A1 P00352 2/20 0.56
TLR2 O60603 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
FABP4 P15090 2/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutanol SCHEMBL27494208 1.00 TSHR (0.63) TSHRLMNANFKB1PMP22GPR84
Stearic Acid SCHEMBL9728490 0.91 GPR84 (0.74) TSHRLMNAGPR84FFAR1FFAR4
SCHEMBL31036870 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Pimelic Acid SCHEMBL30288580 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Propylene Glycol SCHEMBL27855295 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL347212 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Octanedioate SCHEMBL28872523 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Propylene Glycol SCHEMBL5035967 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL347853 0.87 TSHR (0.60) TSHRLMNANFKB1PMP22GPR84
Succinic Acid SCHEMBL28468637 0.86 LMNA (0.56) TSHRLMNANFKB1PMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108558646-A A kind of crystal form of heneicosanedioic acid and preparation method thereof 天津大学 2018-09-21 CN disclosed