Resveratrol 4'-Methyl Ether

Resveratrol 4'-Methyl Ether

SCHEMBL28469037

[2H]C([2H])([2H])Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 7/20 0.76
PTGS1 P23219 7/20 0.76
CYP1A1 P04798 6/20 0.76
CYP1B1 Q16678 5/20 0.76
KDM4E B2RXH2 4/20 0.76
LMNA P02545 3/20 0.76
ALOX12 P18054 1/20 0.76
ALOX5 P09917 5/20 0.59
TTR P02766 4/20 0.59
CYP1A2 P05177 3/20 0.59
MEN1 O00255 3/20 0.59
MAPT P10636 3/20 0.59
KMT2A Q03164 3/20 0.59
ESR1 P03372 3/20 0.59
CYP19A1 P11511 3/20 0.59
ABL1 P00519 3/20 0.59
ABCB1 P08183 3/20 0.59
BCR P11274 3/20 0.59
NQO2 P16083 3/20 0.59
CA12 O43570 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28472010 0.93 PTGS2 (0.67) PTGS2PTGS1CYP1A1CYP1B1KDM4E
SCHEMBL28899386 0.90 PTGS2 (0.73) PTGS2PTGS1CYP1A1CYP1B1KDM4E
SCHEMBL28466511 0.90 PTGS2 (0.73) PTGS2PTGS1CYP1A1CYP1B1KDM4E
Resveratrol 4'-Methyl Ether SCHEMBL4732963 0.86 PTGS2 (1.00) PTGS2PTGS1CYP1A1CYP1B1KDM4E
Resveratrol 4'-Methyl Ether SCHEMBL563261 0.86 PTGS2 (1.00) PTGS2PTGS1CYP1A1CYP1B1KDM4E
Resveratrol 4'-Methyl Ether SCHEMBL563262 0.86 PTGS2 (1.00) PTGS2PTGS1CYP1A1CYP1B1KDM4E
SCHEMBL2516446 0.79 PTGS2 (0.86) PTGS2PTGS1CYP1A1CYP1B1KDM4E
SCHEMBL2516449 0.79 PTGS2 (0.86) PTGS2PTGS1CYP1A1CYP1B1KDM4E
SCHEMBL29662231 0.79 PTGS2 (0.86) PTGS2PTGS1CYP1A1CYP1B1KDM4E
SCHEMBL29652111 0.79 PTGS2 (0.86) PTGS2PTGS1CYP1A1CYP1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111728962-B Resveratrol derivative and medical application thereof in resisting fibrosis 绍兴君科臻元医药科技有限公司 2024-04-30 CN disclosed
CN-111728962-A Resveratrol derivative and medical application of resveratrol derivative in anti-fibrosis 泰州华元医药科技有限公司 2020-10-02 CN disclosed