Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.73 |
| ▸ | TTR | P02766 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466511 | 1.00 | PTGS2 (0.73) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL28472010 | 0.97 | PTGS2 (0.67) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL2516446 | 0.92 | PTGS2 (0.86) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL2516449 | 0.92 | PTGS2 (0.86) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL29652111 | 0.92 | PTGS2 (0.86) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL29662231 | 0.92 | PTGS2 (0.86) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| Resveratrol 4'-Methyl Ether SCHEMBL28469037 | 0.90 | PTGS2 (0.76) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL562336 | 0.84 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL562335 | 0.84 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1ALOX5TTR | |
| SCHEMBL30475363 | 0.84 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1ALOX5TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111728962-B | Resveratrol derivative and medical application thereof in resisting fibrosis | 绍兴君科臻元医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-111728962-A | Resveratrol derivative and medical application of resveratrol derivative in anti-fibrosis | 泰州华元医药科技有限公司 | 2020-10-02 | — | — | CN | disclosed |