SCHEMBL29662231

SCHEMBL29662231

COc1ccc(/C=C/c2cc(O)cc(OC)c2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.86
CYP1A1 P04798 5/20 0.86
CYP1B1 Q16678 5/20 0.86
ALOX5 P09917 5/20 0.86
TTR P02766 3/20 0.86
KDM4E B2RXH2 3/20 0.85
PTGS1 P23219 3/20 0.85
LMNA P02545 1/20 0.85
ALOX12 P18054 1/20 0.85
NQO2 P16083 4/20 0.78
ABL1 P00519 3/20 0.78
BCR P11274 3/20 0.78
ESR1 P03372 2/20 0.78
ABCB1 P08183 2/20 0.78
CYP1A2 P05177 2/20 0.78
AHR P35869 2/20 0.78
CYP19A1 P11511 1/20 0.78
TUBB4A P04350 1/20 0.78
TUBB P07437 1/20 0.78
TUBA3C P0DPH7 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652111 1.00 PTGS2 (0.86) PTGS2CYP1A1CYP1B1ALOX5TTR
SCHEMBL2516446 1.00 PTGS2 (0.86) PTGS2CYP1A1CYP1B1ALOX5TTR
SCHEMBL2516449 1.00 PTGS2 (0.86) PTGS2CYP1A1CYP1B1ALOX5TTR
SCHEMBL562335 0.92 CYP1A1 (1.00) PTGS2CYP1A1CYP1B1ALOX5TTR
SCHEMBL30475363 0.92 CYP1A1 (1.00) PTGS2CYP1A1CYP1B1ALOX5TTR
SCHEMBL562336 0.92 CYP1A1 (1.00) PTGS2CYP1A1CYP1B1ALOX5TTR
Resveratrol 4'-Methyl Ether SCHEMBL4732963 0.92 PTGS2 (1.00) PTGS2CYP1A1CYP1B1ALOX5TTR
Resveratrol 4'-Methyl Ether SCHEMBL563262 0.92 PTGS2 (1.00) PTGS2CYP1A1CYP1B1ALOX5TTR
Resveratrol 4'-Methyl Ether SCHEMBL563261 0.92 PTGS2 (1.00) PTGS2CYP1A1CYP1B1ALOX5TTR
SCHEMBL28899386 0.92 PTGS2 (0.73) PTGS2CYP1A1CYP1B1ALOX5TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US claimed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO claimed
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP disclosed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US disclosed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO disclosed
CN-111728962-B Resveratrol derivative and medical application thereof in resisting fibrosis 绍兴君科臻元医药科技有限公司 2024-04-30 CN disclosed
US-20220185764-A1 Resveratrol derivative and anti-fibrotic method using the same TAIZHOU HUAYUAN MEDICINAL TECH CO. LTD. (CN) 2022-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185764-A1 Resveratrol derivative and anti-fibrotic method using the same REN, RXFP1, RXFP3 PTGS2 2867/4885CYP1A1 724/4885CYP1B1 1367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.