Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.40 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.40 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143747 | 0.75 | TSHR (0.37) | MAPTMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL27418634 | 0.73 | MAPT (0.35) | MAPTMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL4359628 | 0.69 | TSHR (0.53) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL23723493 | 0.69 | CYP3A4 (0.52) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| SCHEMBL28576390 | 0.68 | ALDH1A1 (0.50) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL14336083 | 0.67 | MAPT (0.38) | MAPT | |
| Choline SCHEMBL28900778 | 0.67 | CYP3A4 (0.65) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| SCHEMBL24065972 | 0.66 | MAPT (0.35) | MAPT | |
| SCHEMBL8383208 | 0.65 | LMNA (0.48) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8516094 | 0.65 | CYP3A4 (0.48) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808216-B | Method for extracting hemicellulose from biomass by using eutectic solvent | 北京林业大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-111808216-A | Method for extracting hemicellulose from biomass by using eutectic solvent | 北京林业大学 | 2020-10-23 | — | — | CN | disclosed |