Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471872 | 0.83 | TP53 (0.42) | ACP3ALDH1A1HPGDCYP2C9SMN1; SMN2 | |
| SCHEMBL28469749 | 0.80 | BRD4 (0.50) | MEN1KMT2ACYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL17290331 | 0.80 | MEN1 (0.49) | MEN1KMT2AACP3ADRA1DALDH1A1 | |
| SCHEMBL7565876 | 0.78 | GSK3B (0.40) | MEN1KMT2AADRA1DALDH1A1MAPT | |
| SCHEMBL28860721 | 0.78 | LOXL2 (0.40) | ADRA1DALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL27894375 | 0.78 | ACP3 (0.45) | MEN1KMT2AACP3ADRA1DALDH1A1 | |
| SCHEMBL8028851 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2AACP3ALDH1A1HPGD | |
| SCHEMBL17291147 | 0.76 | KMT2A (0.53) | MEN1KMT2AACP3HPGDSMN1; SMN2 | |
| SCHEMBL28224173 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL22917154 | 0.74 | ACP3 (0.47) | MEN1KMT2AACP3ADRA1DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358831-B | Polysubstituted carbazole derivative and preparation method thereof | 山东师范大学 | 2020-09-29 | — | — | CN | disclosed |