Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040757 | 0.85 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL23535685 | 0.85 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL23559702 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL23559707 | 0.79 | ADORA2A (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL28468125 | 0.78 | LOXL2 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL24337979 | 0.78 | CA12 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7426182 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29950049 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL24338456 | 0.78 | GLA (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29491274 | 0.78 | CA12 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825595-A | Sodium channel blockers | 山东轩竹医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |