Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535685 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL30147699 | 0.89 | MAPT (0.42) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL28926100 | 0.89 | MAPT (0.42) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL28470424 | 0.85 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL23535833 | 0.85 | HCAR3 (0.43) | KDM4EHPGDSCN9A | |
| SCHEMBL30041666 | 0.85 | HCAR3 (0.43) | KDM4EHPGDSCN9A | |
| SCHEMBL29491274 | 0.82 | CA12 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL24337979 | 0.82 | CA12 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL23559707 | 0.80 | ADORA2A (0.47) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL7426182 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115427035-A | ENL/AF9YEATS inhibitors | 洛克菲勒大学 | 2022-12-02 | — | — | CN | disclosed |
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |