Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426182 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL30987624 | 0.88 | MAPT (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL20604896 | 0.88 | MAPT (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| Methyl Nicotinate SCHEMBL30617266 | 0.88 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL23559707 | 0.84 | ADORA2A (0.47) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL31632926 | 0.83 | HCAR3 (0.46) | ALDH1A1KDM4EHPGDJMJD6PARP1 | |
| SCHEMBL24337979 | 0.82 | CA12 (0.46) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL23559702 | 0.82 | KDM4E (0.50) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL24338456 | 0.82 | GLA (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL29491274 | 0.82 | CA12 (0.46) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354195-A1 | METHOD OF SCREENING | UNIV DUNDEE (GB) | 2025-11-20 | — | — | US | disclosed |
| WO-2025129167-A1 | INHIBITORS OF THE SURFACE EXPRESSION OF THE VOLTAGE-GATED SODIUM ION CHANNEL 1.7 (NAV1.7) AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |
| US-20220363694-A1 | N-CYANO-7-AZANORBORNANE DERIVATIVES AND USES THEREOF | AMGEN INC. (US) | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250354195-A1 | METHOD OF SCREENING | PAICS, COASY, ABCG2 | ALDH1A1 275/4885KDM4E 4166/4885HPGD 1782/4885 |
| US-20220363694-A1 | N-CYANO-7-AZANORBORNANE DERIVATIVES AND USES THEREOF | CYP3A7, CYP51A1, NT5C3B | ALDH1A1 793/4885KDM4E 586/4885HPGD 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.