Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472285 | 1.00 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR3EHTR3B | |
| SCHEMBL28468932 | 0.81 | ATM (0.57) | SLC6A2SLC6A4SLC6A3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL28463468 | 0.80 | SIGMAR1 (0.46) | SLC6A2SLC6A4SLC6A3SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28471133 | 0.80 | SIGMAR1 (0.46) | SLC6A2SLC6A4SLC6A3SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28468985 | 0.80 | ATM (0.59) | SLC6A2SLC6A4SLC6A3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL1665569 | 0.80 | ATM (0.59) | SLC6A2SLC6A4SLC6A3HTR3EHTR3B | |
| SCHEMBL28459175 | 0.77 | ALDH1A1 (0.51) | HSD11B1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL7367343 | 0.76 | KMT2A (0.41) | ALDH1A1RAB9APOLBATMMAPT | |
| SCHEMBL22365585 | 0.75 | ROCK2 (0.47) | HSD11B1ALDH1A1GRM2NPC1RAB9A | |
| SCHEMBL8531016 | 0.74 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107174584-B | Application of piperazine structure-containing compound in preparation of LSD1 inhibitor | 福建金乐医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |