SCHEMBL28472008

SCHEMBL28472008

NC(=O)c1ccc(C(=O)Nc2ccsc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.53
KMT2A Q03164 3/20 0.53
MAPT P10636 2/20 0.53
NAMPT P43490 1/20 0.52
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
KDM4E B2RXH2 3/20 0.49
MEN1 O00255 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
BCAT2 O15382 1/20 0.49
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
APEX1 P27695 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PLAU P00749 2/20 0.46
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27652921 0.82 KMT2A (0.57) HPGDKMT2AMAPTNAMPTNPC1
SCHEMBL27652922 0.82 PTPN1 (0.61) HPGDKMT2ANAMPTNPC1RAB9A
SCHEMBL4481913 0.81 HPGD (0.71) HPGDKMT2AMAPTNAMPTNPC1
SCHEMBL27652918 0.81 HDAC6 (0.54) HPGDKMT2ANAMPTNPC1RAB9A
SCHEMBL27652929 0.81 HPGD (0.76) HPGDKMT2ANAMPTNPC1RAB9A
SCHEMBL13210699 0.81 KMT2A (0.73) KMT2AMAPTNPC1RAB9AKDM4E
SCHEMBL3557771 0.79 GAA (0.67) HPGDKMT2AMAPTNAMPTNPC1
SCHEMBL27672996 0.78 KCNK3 (0.57) HPGDMAPTNAMPTNPC1RAB9A
SCHEMBL27652923 0.77 ADORA3 (0.56) HPGDKMT2AMAPTNAMPTNPC1
SCHEMBL27673000 0.77 ROCK2 (0.49) HPGDKMT2ANAMPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111837250-B Organic material and photoelectric conversion element 株式会社理光 2023-11-28 CN disclosed
CN-109608475-B A '-pi-A' type organic small molecule and preparation method and application thereof 湘潭大学 2021-04-27 CN disclosed
CN-111837250-A Organic material and photoelectric conversion element 株式会社理光 2020-10-27 CN disclosed