Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29533755 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL24606355 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL8107900 | 0.76 | ALDH1A1 (0.95) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL29386543 | 0.76 | ALDH1A1 (0.95) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL668026 | 0.74 | ALDH1A1 (0.97) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL12123672 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL653025 | 0.73 | PKM (0.87) | ALDH1A1HPGDTSHRPKMCTNNB1 | |
| SCHEMBL22638785 | 0.72 | ALDH1A1 (0.97) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL29773050 | 0.72 | ALDH1A1 (0.97) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL22651604 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTTP53ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072398-A | Compounds that inhibit TDG activity | 上海仕谱生物科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-111909138-A | Compounds that inhibit TDG activity | 上海仕谱生物科技有限公司 | 2020-11-10 | — | — | CN | disclosed |