Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.45 |
| ▸ | WNT3A | P56704 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24606355 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL28472102 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL21770322 | 0.78 | HPGD (0.55) | ALDH1A1MAPTTP53L3MBTL1LMNA | |
| SCHEMBL13114817 | 0.72 | ALDH1A1 (0.55) | ALDH1A1HTTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL8107900 | 0.70 | ALDH1A1 (0.95) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL31421218 | 0.70 | HCRTR2 (0.40) | ALDH1A1LMNAMAOBKDM4EGAA | |
| SCHEMBL29386543 | 0.70 | ALDH1A1 (0.95) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL10031397 | 0.69 | KDM4E (0.55) | ALDH1A1MAPTTP53LMNAHPGD | |
| SCHEMBL668026 | 0.69 | ALDH1A1 (0.97) | ALDH1A1MAPTHTTTP53ALDH3A1 | |
| SCHEMBL12123672 | 0.69 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTTP53ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213070-A1 | COMPOUNDS INHIBITING TDG ACTIVITY | Epitas Biosciences (shanghai) Co., Ltd. (CN) | 2022-07-07 | — | — | US | disclosed |
| EP-3971180-A1 | COMPOUNDS INHIBITING TDG ACTIVITY | Epitas Biosciences (Shanghai) Co., Ltd. (CN) | 2022-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213070-A1 | COMPOUNDS INHIBITING TDG ACTIVITY | TDO2, TFPI, PPIG | ALDH1A1 1309/4885MAPT 3200/4885HTT 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.