Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2843408 | 0.92 | PAOX (0.43) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL2845937 | 0.88 | PAOX (0.37) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL13187897 | 0.88 | PAOX (0.37) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL5188594 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KDM4EPOLB | |
| SCHEMBL2839045 | 0.84 | PAOX (0.39) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL18024081 | 0.84 | PAOX (0.43) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL25477672 | 0.83 | HRH3 (0.46) | SIGMAR1TSHRALDH1A1POLB | |
| SCHEMBL17495643 | 0.83 | HRH3 (0.46) | SIGMAR1TSHRALDH1A1POLB | |
| SCHEMBL24654746 | 0.83 | KDM4E (0.37) | PAOXSIGMAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL2844514 | 0.82 | HRH3 (0.50) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092737-B1 | Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin | TOSOH CORP (JP) | 2003-09-24 | — | — | EP | claimed |
| US-6596663-B1 | Reacting a polyol with an organic polyisocyanate in the presence of a diamine catalyst and, if necessary, a blowing agent, a surfactant, a cross-linking agent | TOSOH CORPORATION (JP) | 2003-07-22 | — | — | US | claimed |
| EP-1092737-A2 | Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin | Tosoh Corporation (JP) | 2001-04-18 | — | — | EP | claimed |
| US-8877825-B2 | Catalyst composition for production of polyurethane resin and method for producing polyurethane resin | TOSOH CORPORATION (JP) | 2014-11-04 | — | — | US | disclosed |
| EP-2050775-B1 | CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN | TOSOH CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-20100130629-A1 | CATALYST COMPOSITION FOR PRODUCTION OF POLYURETHANE RESIN AND METHOD FOR PRODUCING POLYURETHANE RESIN (AS AMENDED) | TOSOH CORPORATION (JP) | 2010-05-27 | — | — | US | disclosed |
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| EP-2050775-A1 | CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN | Tosoh Corporation (JP) | 2009-04-22 | — | — | EP | disclosed |
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| US-7097854-B2 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | MEDIGENE ONCOLOGY GMBH (DE) | 2006-08-29 | — | — | US | disclosed |
| US-20030236266-A1 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | ROCHE DIAGNOSTICS GMBH | 2003-12-25 | — | — | US | disclosed |
| EP-1092737-B1 | Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin | TOSOH CORP (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| US-6596663-B1 | Reacting a polyol with an organic polyisocyanate in the presence of a diamine catalyst and, if necessary, a blowing agent, a surfactant, a cross-linking agent | TOSOH CORPORATION (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |
| EP-1092737-A2 | Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin | Tosoh Corporation (JP) | 2001-04-18 | — | — | EP | disclosed |
| EP-0927174-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MediGene Oncology GmbH (DE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011082-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236266-A1 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | ADH1C, ADH1A, ADH5 | PAOX 393/4885SIGMAR1 126/4885CHRM2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.