Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122885 | 1.00 | LMNA (0.52) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL3122880 | 1.00 | LMNA (0.52) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL710656 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL29721816 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL1223756 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL1223761 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL6265289 | 0.82 | ERCC5 (0.46) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7770355 | 0.82 | ERCC5 (0.46) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7770353 | 0.82 | ERCC5 (0.46) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4787174 | 0.81 | HPGD (0.56) | LMNATSHRHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093325-A2 | POLYMORPHS OF 3-(E)-2-{2-[6-(2-CYANOPHENOXY) PYRIMIDIN-4-YLOXY]PHENYL}-3-METHOXYACRYLATE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2008-08-07 | — | — | WO | disclosed |
| US-6777412-B2 | PYRIMIDIN-4-YLOXY)PHENYL)-3-METHOXYPROPENOATE DERIVATIVES | SYNGENTA LIMITED (GB) | 2004-08-17 | — | — | US | disclosed |
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | CLOUGH JOHN MARTIN (GB) | 2004-05-13 | — | — | US | disclosed |
| US-6613773-B2 | Pyrimidinyloxyphenyl-3-alkoxypropenoates derivatives | SYNGENTA LIMITED (GB) | 2003-09-02 | — | — | US | disclosed |
| US-20030060626-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
| US-6465457-B1 | CONTROLLING PATHOGENS ON PLANTS OR SEEDS | ZENECA LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| EP-0664798-B1 | THIADIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES OR INSECTICIDES | ZENECA LTD (GB) | 1999-12-29 | — | — | EP | disclosed |
| US-5942509-A | 2-(TRIAZINYLOXY(OR THIO)PHENYL)-SUBSTITUTED METHYL 3-METHOXY-2-PROPENOATE | ZENECA LIMITED (GB) | 1999-08-24 | — | — | US | disclosed |
| US-5939563-A | FUNGICIDES | ZENECA LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |
| US-5777162-A | Intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1998-07-07 | — | — | US | disclosed |
| EP-0667865-A1 | OXA- AND THIADIAZOLE DERIVATIVES USED AS INSECTICIDES AND FUNGICIDES. | ZENECA LTD (GB) | 1995-08-23 | — | — | EP | disclosed |
| EP-0664798-A1 | THIA- AND OXADIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES OR INSECTICIDES | ZENECA LIMITED (GB) | 1995-08-02 | — | — | EP | disclosed |
| US-5438066-A | Fungicide, insecticide, miticide and pesticide | ZENECA LIMITED (GB) | 1995-08-01 | — | — | US | disclosed |
| WO-1995005368-A1 | THIA- AND OXADIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES OR INSECTICIDES | ZENECA LIMITED (GB) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994010159-A1 | OXA- AND THIADIAZOLE DERIVATIVES USED AS INSECTICIDES AND FUNGICIDES | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |
| EP-0483985-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-05-06 | — | — | EP | disclosed |
| EP-0468695-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468684-A2 | Propenoic acid derivatives, process for their preparation and their use as fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
| EP-0405782-A1 | Fungicides | ZENECA LIMITED (GB) | 1991-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | DDT, SQOR, TH | LMNA 3076/4885TSHR 946/4885HPGD 1482/4885 |
| US-20030060626-A1 | Fungicides | CYP51A1, CYP1A1, CYP1A2 | LMNA 2821/4885TSHR 2595/4885HPGD 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.