SCHEMBL3122885

SCHEMBL3122885

COC=C(C(=O)O)c1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
TSHR P16473 2/20 0.52
HPGD P15428 8/20 0.48
KDM4E B2RXH2 7/20 0.48
ALDH1A1 P00352 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
HMGB1 P09429 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
HSD17B10 Q99714 4/20 0.44
ALOX15 P16050 2/20 0.44
CYP2C19 P33261 3/20 0.42
CYP3A4 P08684 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3122880 1.00 LMNA (0.52) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL4787172 1.00 LMNA (0.52) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL710656 0.84 LMNA (0.55) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL29721816 0.84 LMNA (0.55) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL1223756 0.84 LMNA (0.55) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL1223761 0.84 LMNA (0.55) LMNATSHRHPGDKDM4EALDH1A1
SCHEMBL6265289 0.82 ERCC5 (0.46) LMNAHPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL7770355 0.82 ERCC5 (0.46) LMNAHPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL7770353 0.82 ERCC5 (0.46) LMNAHPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL4787174 0.81 HPGD (0.56) LMNATSHRHPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5728729-A 3-methoxy-2-phenylacrylic acid esters used as pest-control agents, especially as fungicides BAYER AKTIENGESELLSCHAFT (DE) 1998-03-17 US claimed
EP-0699183-A1 3-METHOXY-2-PHENYLACRYLIC ACID ESTERS USED AS PEST-CONTROL AGENTS, ESPECIALLY AS FUNGICIDES BAYER AG (DE) 1996-03-06 EP claimed
WO-1994026705-A1 3-METHOXY-2-PHENYLACRYLIC ACID ESTERS USED AS PEST-CONTROL AGENTS, ESPECIALLY AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1994-11-24 WO claimed
US-11882828-B2 Mosquito vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 US disclosed
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 US disclosed
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 US disclosed
EP-3302056-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME Syngenta Participations AG (CH) 2018-04-11 EP disclosed
WO-2016193267-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2016-12-08 WO disclosed
EP-2308825-B1 Process for the preparation of an intermediate for azoxystrobin SYNGENTA LTD (GB) 2014-05-21 EP disclosed
EP-1891020-B1 PROCESSES FOR THE PREPARATION OF AZOXYSTROBIN USING DABCO AS A CATALYST AND NOVEL INTERMEDIATES USED IN THE PROCESSES SYNGENTA LTD (GB) 2013-06-05 EP disclosed
US-8278445-B2 Preparation methods of azoxystrobin and its analogs NUTRICHEM COMPANY LIMITED (CN) 2012-10-02 US disclosed
EP-0468695-A1 Fungicides ZENECA LIMITED (GB) 1992-01-29 EP disclosed
US-5057146-A CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-15 US disclosed
US-5034388-A Acrylic acid derivatives substituted with benzene IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-07-23 US disclosed
EP-0405782-A1 Fungicides ZENECA LIMITED (GB) 1991-01-02 EP disclosed
EP-0391451-A1 Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-10 EP disclosed
EP-0387923-A2 Fungicides ZENECA LIMITED (GB) 1990-09-19 EP disclosed
US-4931438-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-05 US disclosed
US-4870075-A AGRICULTURE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-26 US disclosed
EP-0242081-A1 Fungicides ZENECA LIMITED (GB) 1987-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 LMNA 2239/4885TSHR 4878/4885HPGD 3073/4885
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 LMNA 2239/4885TSHR 4878/4885HPGD 3073/4885
US-11882828-B2 Mosquito vector control compositions, methods and products utilizing same DDT, MLEC, MSMO1 LMNA 2239/4885TSHR 4878/4885HPGD 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.