Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28477691 | 0.84 | POLB (0.41) | POLBGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2635588 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2KEAP1POLBKDM4EALDH1A1 | |
| SCHEMBL503668 | 0.76 | KDM4E (0.57) | SMN1; SMN2KEAP1POLBGAAKDM4E | |
| SCHEMBL22840863 | 0.74 | KDM4E (0.55) | SMN1; SMN2KEAP1POLBGAAKDM4E | |
| SCHEMBL525957 | 0.74 | KDM4E (0.55) | SMN1; SMN2KEAP1POLBGAAKDM4E | |
| SCHEMBL18024033 | 0.70 | KDM4E (0.53) | SMN1; SMN2KEAP1POLBGAAKDM4E | |
| SCHEMBL111438 | 0.67 | TSHR (0.58) | SMN1; SMN2KEAP1KDM4EALDH1A1TSHR | |
| SCHEMBL11128458 | 0.67 | HSD17B10 (0.44) | SMN1; SMN2KEAP1POLBKDM4EALDH1A1 | |
| SCHEMBL28930625 | 0.67 | SMN1; SMN2 (0.70) | SMN1; SMN2KEAP1KDM4EALDH1A1TSHR | |
| SCHEMBL4376068 | 0.67 | ALDH1A1 (0.53) | SMN1; SMN2KEAP1POLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741949-A | Method for the continuous separation by distillation of a mixture comprising Morpholine (MO), monoaminodiglycol (ADG), ammonia, water and Methoxyethanol (MOE) | 巴斯夫欧洲公司 | 2020-10-02 | — | — | CN | disclosed |