Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ASPH | Q12797 | 3/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725412 | 0.80 | MAPK1 (0.44) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL30433741 | 0.80 | MAPK1 (0.44) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL3408592 | 0.78 | KMO (0.52) | KDM4EASPHKDM8KMOALDH1A1 | |
| SCHEMBL29712296 | 0.78 | KMO (0.52) | KDM4EASPHKDM8KMOALDH1A1 | |
| SCHEMBL21616724 | 0.77 | KMO (0.40) | KDM4EASPHKDM8KMOGPR35 | |
| SCHEMBL2262851 | 0.77 | KDM4E (0.47) | KDM4EASPHKDM8KMOALDH1A1 | |
| SCHEMBL3240453 | 0.75 | ASPH (0.55) | KDM4EASPHKDM8KMOALDH1A1 | |
| SCHEMBL3408048 | 0.75 | KDM4E (0.46) | KDM4EASPHKDM8KMOALDH1A1 | |
| SCHEMBL935259 | 0.73 | KMO (0.51) | KDM4EASPHKDM8KMOALDH1A1 | |
| SCHEMBL15544791 | 0.73 | KDM4E (0.47) | KDM4EASPHKDM8KMOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-A | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2020-11-03 | — | — | CN | disclosed |