Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 4/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.35 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622928 | 0.85 | MAPK1 (0.44) | KDM4EMAPK1L3MBTL1 | |
| SCHEMBL21616774 | 0.80 | GPR35 (0.43) | KMOKDM4EMAPK1L3MBTL1ASPH | |
| SCHEMBL30340453 | 0.80 | GPR35 (0.43) | KMOKDM4EMAPK1L3MBTL1ASPH | |
| SCHEMBL28475255 | 0.77 | KDM4E (0.42) | KMOKDM4EASPHKDM8GPR35 | |
| SCHEMBL21616740 | 0.76 | HCAR2 (0.43) | KDM4EMAPK1L3MBTL1ASPHKDM8 | |
| SCHEMBL10709062 | 0.76 | KMO (0.55) | KMOKDM4EMAPK1L3MBTL1ASPH | |
| SCHEMBL24660110 | 0.75 | ASPH (0.40) | KMOKDM4EMAPK1L3MBTL1ASPH | |
| SCHEMBL3408592 | 0.74 | KMO (0.52) | KMOKDM4EASPHKDM8GPR35 | |
| SCHEMBL29712296 | 0.74 | KMO (0.52) | KMOKDM4EASPHKDM8GPR35 | |
| SCHEMBL935259 | 0.73 | KMO (0.51) | KMOKDM4EMAPK1L3MBTL1ASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111886219-A | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2020-11-03 | — | — | CN | disclosed |
| WO-2020011209-A1 | IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2020-01-16 | — | — | WO | disclosed |
| WO-2020011209-A1 | IMMUNOSUPPRESSIVE AGENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2020-01-16 | — | — | WO | disclosed |