Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.68 |
| ▸ | NPC1 | O15118 | 9/20 | 0.68 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | MMP8 | P22894 | 3/20 | 0.55 |
| ▸ | MMP13 | P45452 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745692 | 0.85 | CHEK2 (0.60) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL11746348 | 0.82 | CHEK2 (0.53) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL28475614 | 0.82 | NPC1 (0.56) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL28483088 | 0.82 | NPC1 (0.71) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL4670013 | 0.81 | NPBWR1 (0.56) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL15413801 | 0.81 | NPBWR1 (0.56) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL31679090 | 0.81 | NPBWR1 (1.00) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL2308775 | 0.81 | NPBWR1 (0.79) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL2245102 | 0.81 | NPBWR1 (1.00) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 | |
| SCHEMBL3132123 | 0.78 | NPC1 (0.68) | RAB9AMAPTNPC1NPBWR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471019-B | 5, 6-dinitrobenzimidazole compound and synthesis method and application thereof | 浙江工业大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-111471019-A | 5, 6-dinitrobenzimidazole compound and synthesis method and application thereof | 浙江工业大学 | 2020-07-31 | — | — | CN | disclosed |