Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473486 | 0.91 | SCN9A (0.41) | KDRMRGPRX4SCN9APDK1PDK2 | |
| SCHEMBL28478162 | 0.83 | SCN9A (0.51) | SCN9ASCN5A | |
| SCHEMBL28473635 | 0.78 | L3MBTL1 (0.46) | MEN1KMT2AKDM4EL3MBTL1MAPT | |
| SCHEMBL28472884 | 0.73 | TLR8 (0.41) | KMT2AMAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL7658563 | 0.72 | ALDH1A1 (0.43) | KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28468125 | 0.72 | LOXL2 (0.46) | KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL27272748 | 0.72 | SLC22A12 (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL7656202 | 0.72 | KDM4E (0.38) | SCN9ASCN5AKMT2AKDM4EMAPT | |
| SCHEMBL30204298 | 0.71 | NPC1 (0.54) | SCN9APDK2KDM4EL3MBTL1CYP2D6 | |
| SCHEMBL28479309 | 0.70 | MAPT (0.39) | MRGPRX4SCN9ASCN5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825595-A | Sodium channel blockers | 山东轩竹医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |