Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30372451 | 0.95 | GAA (0.37) | GAAALDH1A1TOP1FABP4FABP5 | |
| SCHEMBL15137506 | 0.82 | POLB (0.32) | GAAAPEX1POLB | |
| SCHEMBL3878105 | 0.81 | DRD2 (0.38) | GAAALDH1A1TBXA2RMEN1POLB | |
| SCHEMBL1714490 | 0.78 | USP2 (0.38) | APEX1USP2HDAC1HDAC6 | |
| SCHEMBL29738288 | 0.77 | DRD2 (0.38) | GAAALDH1A1MEN1POLBKMT2A | |
| SCHEMBL14454734 | 0.77 | FABP4 (0.41) | GAATOP1FABP4FABP5USP2 | |
| SCHEMBL4591369 | 0.77 | DRD2 (0.38) | GAAALDH1A1MEN1POLBKMT2A | |
| SCHEMBL12136664 | 0.77 | GAA (0.32) | GAAALDH1A1TOP1MEN1POLB | |
| SCHEMBL18439061 | 0.77 | HTR7 (0.32) | MEN1KMT2A | |
| SCHEMBL997083 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129293-A1 | Near Infrared Imaging Agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2010-05-27 | — | — | US | disclosed |
| US-7655217-B2 | Near infrared imaging agent | Institut fur Diagnosikforschung GmbH (DE) | 2010-02-02 | — | — | US | disclosed |
| US-7445767-B2 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20060165599-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060165598-A1 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2006-07-27 | — | — | US | disclosed |
| US-7025949-B2 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2006-04-11 | — | — | US | disclosed |
| US-6926885-B2 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2005-08-09 | — | — | US | disclosed |
| US-20050169844-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-08-04 | — | — | US | disclosed |
| US-6913743-B2 | As contrast medium for fluorescence and transillumination diagnostics; drugs | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-07-05 | — | — | US | disclosed |
| US-20050106106-A1 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1181940-B1 | In vivo diagnostics by near infrared radiation | DIAGNOSTIKFORSCHUNG INST (DE) | 2004-12-22 | — | — | EP | disclosed |
| US-20030170179-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITA (COPY) | 2003-09-11 | — | — | US | disclosed |
| EP-0796111-B1 | IN-VIVO DIAGNOSTIC PROCESS BY NEAR INFRARED RADIATION USING CYANINE DYES | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20030026763-A1 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN | 2003-02-06 | — | — | US | disclosed |
| EP-1181940-A2 | In vivo diagnostics by near infrared radiation | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2002-02-27 | — | — | EP | disclosed |
| US-20010055567-A1 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN | 2001-12-27 | — | — | US | disclosed |
| US-6258340-B1 | USING WATER-SOLUBLE DYES AND THEIR BIOMOLECULE ADDUCTS EACH HAVING SPECIFIC PHOTOPHYSICAL AND PHARMOCHEMICAL PROPERTIES | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| US-6083485-A | USEING WATER-SOLUBLE DYES AND THEIR BIOMOLECULE ADDUCTS AS CONTRAST MEDIUM FOR FLUORESCENCE AND TRANSILLUMINATION DIAGNOSTICS IN THE NEAR INFRARED RADIATION RANGE | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2000-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165598-A1 | In-vivo diagnostic method by near infrared radiation | GUSB, CYBA, ABCG2 | GAA 1632/4885ALDH1A1 127/4885TOP1 491/4885 |
| US-20100129293-A1 | Near Infrared Imaging Agent | UGT1A10, ABCG2, SLCO1B1 | GAA 1404/4885ALDH1A1 152/4885TOP1 488/4885 |
| US-20050106106-A1 | In-vivo diagnostic method by near infrared radiation | GUSB, CYBA, ABCG2 | GAA 1632/4885ALDH1A1 127/4885TOP1 491/4885 |
| US-20050169844-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | GAA 1404/4885ALDH1A1 152/4885TOP1 488/4885 |
| US-20060165599-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | GAA 1404/4885ALDH1A1 152/4885TOP1 488/4885 |
| US-20010055567-A1 | In-vivo diagnostic method by means of near infrared radiation | GUSB, ABCG2, SLCO1B1 | GAA 1100/4885ALDH1A1 153/4885TOP1 791/4885 |
| US-20030026763-A1 | In-vivo diagnostic method by means of near infrared radiation | GUSB, ABCG2, SLCO1B1 | GAA 1100/4885ALDH1A1 153/4885TOP1 791/4885 |
| US-20030170179-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | GAA 1404/4885ALDH1A1 152/4885TOP1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.