⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15137506 | 0.92 | POLB (0.32) | — | |
| SCHEMBL15137568 | 0.88 | — | — | |
| SCHEMBL6018477 | 0.87 | MEN1 (0.35) | — | |
| SCHEMBL881399 | 0.86 | APEX1 (0.34) | — | |
| SCHEMBL2677869 | 0.84 | MEN1 (0.36) | — | |
| SCHEMBL15417350 | 0.80 | PKM (0.34) | — | |
| SCHEMBL18772444 | 0.80 | RXRA (0.32) | — | |
| SCHEMBL15417320 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL27699697 | 0.79 | KMT2A (0.37) | — | |
| SCHEMBL2847745 | 0.76 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874871-B1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LTD (GB) | 2012-10-03 | — | — | EP | disclosed |
| EP-2270106-A2 | Indolium compounds containing fluoro-substituents | GE Healthcare UK Limited (GB) | 2011-01-05 | — | — | EP | disclosed |
| US-20100249385-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-7767829-B2 | Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2010-08-03 | — | — | US | disclosed |
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | US | disclosed |