Formic Acid

Formic Acid

SCHEMBL28477809

Cc1ccc(C)c2oc([Na])nc12.O=CO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARA P10276 4/20 0.39
RARB P10826 4/20 0.39
RARG P13631 4/20 0.39
ELANE P08246 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13089971 0.69 ELANE (0.46) RARARARBRARGELANE
SCHEMBL29809645 0.68 RARA (0.50) RARARARBRARG
SCHEMBL17864535 0.68 RARA (0.50) RARARARBRARG
SCHEMBL18873566 0.66 RARA (0.35) RARARARBRARGELANE
SCHEMBL19583308 0.66 RARA (0.42) RARARARBRARGELANE
SCHEMBL18873197 0.62 RARA (0.35) RARARARBRARG
SCHEMBL9076045 0.62 ALDH1A1 (0.42) RARARARBRARGELANE
SCHEMBL17059011 0.61 RARA (0.50) RARARARBRARG
SCHEMBL21474855 0.60 RARA (0.46) RARARARBRARG
SCHEMBL21474634 0.60 RARA (0.46) RARARARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207488-B Bicyclic heteroaryl-benzoic acid compounds as retinoic acid receptor beta (RAR) agonists 伦敦皇家学院 2020-11-17 CN disclosed