SCHEMBL13089971

SCHEMBL13089971

Cc1nc2c(C)ccc(C)c2o1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.46
RARA P10276 4/20 0.40
RARB P10826 4/20 0.40
RARG P13631 4/20 0.40
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12052974 0.80 GPR55 (0.40) ELANERARARARBRARGKDM4E
SCHEMBL12422704 0.77 ELANE (0.37) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL18873197 0.73 RARA (0.35) RARARARBRARG
SCHEMBL18873566 0.73 RARA (0.35) ELANERARARARBRARG
SCHEMBL17864535 0.71 RARA (0.50) RARARARBRARGKDM4EMEN1
SCHEMBL17059011 0.71 RARA (0.50) RARARARBRARGKDM4EALDH1A1
SCHEMBL29809645 0.71 RARA (0.50) RARARARBRARGKDM4EMEN1
SCHEMBL21474634 0.70 RARA (0.46) RARARARBRARGKDM4EMEN1
Formic Acid SCHEMBL28477809 0.69 RARA (0.39) ELANERARARARBRARG
SCHEMBL19267565 0.69 KDM4E (0.34) ELANEKDM4EMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200165519-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND RETARDATION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-28 US disclosed
US-9927625-B2 Birefringent lens material for stereoscopic image display device and method for producing birefringent lens for stereoscopic image display device DIC CORPORATION (JP) 2018-03-27 US disclosed
US-9927625-B2 Birefringent lens material for stereoscopic image display device and method for producing birefringent lens for stereoscopic image display device DIC CORPORATION (JP) 2018-03-27 US disclosed
US-20180037817-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2018-02-08 US disclosed
US-20180037817-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2018-02-08 US disclosed
US-20170369783-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-12-28 US disclosed
US-20170362508-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-12-21 US disclosed
US-20170362508-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-12-21 US disclosed
US-9599829-B2 Birefringent lens material for stereoscopic image display device and method for producing birefringent lens for stereoscopic image display device DIC CORPORATION (JP) 2017-03-21 US disclosed
US-9527828-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-12-27 US disclosed
US-9527828-B2 Method for expanding hematopoietic stem cells using heterocyclic compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-12-27 US disclosed
US-9328085-B2 Heterocyclic compounds and expansion agents for hematopoietic stem cells NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-03 US disclosed
US-9328085-B2 Heterocyclic compounds and expansion agents for hematopoietic stem cells NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-03 US disclosed
US-20150030973-A1 BIREFRINGENT LENS MATERIAL FOR STEREOSCOPIC IMAGE DISPLAY DEVICE AND METHOD FOR PRODUCING BIREFRINGENT LENS FOR STEREOSCOPIC IMAGE DISPLAY DEVICE DIC CORPORATION (JP) 2015-01-29 US disclosed
US-20130309411-A1 BIREFRINGENT LENS MATERIAL FOR STEREOSCOPIC IMAGE DISPLAY DEVICE AND METHOD FOR PRODUCING BIREFRINGENT LENS FOR STEREOSCOPIC IMAGE DISPLAY DEVICE DIC CORPORATION (JP) 2013-11-21 US disclosed
US-20130245255-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-20130245255-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-20100266556-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2010-10-21 US disclosed
US-20100266556-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245255-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS HCLS1, RUNX1, RCC1 ELANE 1721/4885RARA 1203/4885RARB 1448/4885
US-20100266556-A1 METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND HCLS1, RUNX1, ACIN1 ELANE 2151/4885RARA 1719/4885RARB 1844/4885
US-20170362508-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY PBDC1, RCC1, PUF60 ELANE 1967/4885RARA 1060/4885RARB 1860/4885
US-20170369783-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT VIM, SMCHD1, SMC4 ELANE 3315/4885RARA 2186/4885RARB 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.